GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
Cacao
Contributes to | GO:0072353 | cellular age-dependent response to reactive oxygen species | PMID:19221591 | IDA: Inferred from Direct Assay | P | |||
This annotation made on page: By: Detomas1 (group Team Best in the NIT) on 2013-03-31 16:55:45 CDT. |
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Entry Type | Challenging User,Group | Time/Date | Challenge Reason | Points/Assessment |
---|---|---|---|---|
Challenge | Detomas1, Team Best in the NIT | 2013-04-20 21:35:53 CDT | The evidence code should be IMP | 2 |
Challenge | Thoma850, Team Gene Simmons 2013 | 2013-04-07 14:11:33 CDT | Go term should be GO:0001315 Also, for figures 1 and 2 make sure to mention that it was a hetrozygous mutation of dOpa1. Additionally Figure 3, shows Heterozygous dOpa1 mutation impairs mitochondrial bioenergetics. Furthermore, in figure 3 there was a deficiency in aconitase which is a crucial enzyme that has Fe-S proteins that function in the ETC. In figure 2 as stated that hetrozygous dOpa1 mutation there is an increase in ROS, in turn ROS damages the ETC, which leads to ETC dysfunction as seen in figure 3 where mitochondrial bioenergetics and aconitase function were both affected. In addition, with having aconitase function decreased it can lead to respiratory problems leading to an increase in ROS. | 0 |
Private Assessment | JimHu | 2013-04-28 19:58:06 CDT | You need to be an instructor to view these notes. | Unacceptable ✗ Go term |
Public Assessment | JimHu | 2013-04-28 19:57:25 CDT | As noted in Thoma850s challenge, annotation of this paper using the figures cited would require response to terms, which are not allowed for CACAO. | Unacceptable ✗ Go term |
Public Assessment | DanielRenfro | 2013-04-20 21:35:53 CDT | This annotation has been flagged because it has been edited since last assessment | Flagged |
Private Assessment | Suzialeksander | 2013-04-07 21:05:37 CDT | You need to be an instructor to view these notes. | Requires Changes |
Public Assessment | DanielRenfro | 2013-04-07 14:11:33 CDT | This annotation has been flagged because it has been edited since last assessment | Flagged |
Private Assessment | Bmcintosh | 2013-04-03 13:06:08 CDT | You need to be an instructor to view these notes. | Requires Changes ✔ Protein ✔ Publication ✗ Qualifier ✗ Go term ✗ Evidence ✔ With/From ✗ Notes ✔ Unique/Original |