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Cacao

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The row for this annotation cannot be found. This might be due to a row or page getting deleted.

Contributes toGO:0072353cellular age-dependent response to reactive oxygen speciesPMID:19221591IDA: Inferred from Direct Assay P
This annotation made on page:
By: Detomas1 (group Team Best in the NIT) on 2013-03-31 16:55:45 CDT.




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeDetomas1,
Team Best in the NIT
2013-04-20 21:35:53 CDT

The evidence code should be IMP

2
ChallengeThoma850,
Team Gene Simmons 2013
2013-04-07 14:11:33 CDT

Go term should be GO:0001315 Also, for figures 1 and 2 make sure to mention that it was a hetrozygous mutation of dOpa1. Additionally Figure 3, shows Heterozygous dOpa1 mutation impairs mitochondrial bioenergetics. Furthermore, in figure 3 there was a deficiency in aconitase which is a crucial enzyme that has Fe-S proteins that function in the ETC. In figure 2 as stated that hetrozygous dOpa1 mutation there is an increase in ROS, in turn ROS damages the ETC, which leads to ETC dysfunction as seen in figure 3 where mitochondrial bioenergetics and aconitase function were both affected. In addition, with having aconitase function decreased it can lead to respiratory problems leading to an increase in ROS.

0
Private
Assessment
JimHu2013-04-28 19:58:06 CDTYou need to be an instructor to view these notes.Unacceptable
Go term
Public
Assessment
JimHu2013-04-28 19:57:25 CDT

As noted in Thoma850s challenge, annotation of this paper using the figures cited would require response to terms, which are not allowed for CACAO.

Unacceptable
Go term
Public
Assessment
DanielRenfro2013-04-20 21:35:53 CDT

This annotation has been flagged because it has been edited since last assessment

Flagged
Private
Assessment
Suzialeksander2013-04-07 21:05:37 CDTYou need to be an instructor to view these notes.Requires Changes
Public
Assessment
DanielRenfro2013-04-07 14:11:33 CDT

This annotation has been flagged because it has been edited since last assessment

Flagged
Private
Assessment
Bmcintosh2013-04-03 13:06:08 CDTYou need to be an instructor to view these notes.Requires Changes
Protein
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Go term
Evidence
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