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Cacao

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GO:0005783endoplasmic reticulumPMID:20188343IMP: Inferred from Mutant Phenotype C
This annotation made on page: HUMAN:SERPH
By: Bhatt001 (group Team The Histones) on 2012-04-01 17:38:58 CDT.




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeImumm,
Team IT
2012-04-03 19:24:13 CDT

The go term is correctly used in this instance, specifically in part C of figure 1. However, I think that the GO evidence code should be changed to IDA, because the portion of the figure that pertains to the protein being localized to the ER deals with immunocytochemistry (ICC). ICC uses selective antibodies to bind to protein antigens and then are later located to determine where the proteins resides. IDA pertains to a physical interaction or binding assays.

5
ChallengeHilaryann0524,
Team Unicorn
2012-04-03 19:05:59 CDT

This is a poor GO term. It should be replaced with GO:0031647. This GO term is regulation of protein stability.

0
Public
Assessment
Mkline2012-04-04 13:01:13 CDT

I think at least one additional annotation could be used including Fig 3 as evidence regarding the protein's actual function. The notes should be changed for this annotation to refer only to the part of Fig 3 that deals with this protein's location.

Requires Changes
Private
Assessment
Mkline2012-04-04 12:59:59 CDTYou need to be an instructor to view these notes.Requires Changes