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GO:0060618nipple developmentIMP: Inferred from Mutant Phenotype P
This annotation made on page: MOUSE:REL1
By: JmicG (group Team Mighty Morphin GO Annotators) on 2011-09-25 17:57:05 CDT.




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeJmicG,
Team Mighty Morphin GO Annotators
2011-09-28 11:21:11 CDT

I'm not sure why, but the PMID reference code was not added correctly. The reference that I obtained the information from is PMID 9886856, "Mice without a Functional Relaxin Gene Are Unable to Deliver Milk to Their Pups."

2
ChallengeBISON,
Team NDSU Bisons
2011-09-28 10:18:51 CDT

Just our of curiosity. THis protein appears to have functions in mammary gland and male gonad development. Is there an explanation how that goes together?

I realize there may not be field to enter this, I just found it interesting. Will check here later, if anybody has an answer.

None, yet.
ChallengeVchhabria,
Team KremlinOnTheCrum
2011-09-27 20:00:01 CDT

I think this is the reference this was referring to PMID 14701741, an article titled Impaired nipple development and parturition in LGR7 knockout mice. In Figure 6, it does have an image of a LGR7 mutant, a mutant in a receptor for relaxin, with abnormal nipple development. The author cites another paper offering a similar phenotype for relaxin deficiency. This paper is inaccessible for free.

None, yet.
ChallengeAlexFrancis,
Team Jimmy Johns
2011-09-27 19:08:53 CDT

No reference code

1
Private
Assessment
Mkline2012-03-23 15:27:45 CDTYou need to be an instructor to view these notes.Acceptable
Private
Assessment
Davidmigl2011-10-04 20:21:39 CDTYou need to be an instructor to view these notes.Requires Changes