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Cacao

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GO:1900119positive regulation of execution phase of apoptosisPMID:25890299IDA: Inferred from Direct Assay P
This annotation made on page: CANLF:A0A0C5E1H5
By: AshFlipp3 (group Team Donuts) on 2018-10-16 12:54:25 CDT.




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeMckaelaAutumn19,
Team BICH
2018-11-06 14:01:09 CST

The UNIPROT ID should be A0A0C5E1H5 because the protein should be tumor suppressor protein p53/p53/cellular tumor antigen p53 because p53 is preforming the biological response that causes the apoptosis. Zhangfei not preforming the apoptosis, but is only affecting the p53 protein and Zhangfei has not been annotated for Canis lupus familiaris on Uniprot.

The GO term should be GO:0010628 (positive regulation of gene expression because p53 is binding to the p53 response element in the plasmid to positively express the report protein CAT (chloramphenicol acetyl transferase).

The notes should be "Figure 1 Part C shows the CAT (chloramphenicol acetyl transferase) expression activity that is positively regulated by the tumor suppressor protein p53/p53/cellular tumor antigen p53 when it binds to the p54 response element in plasmids present in several different Canis lupus familiaris osteosarcoma cell lines exposed to pCAT3B or pCAT3B-p53RE in the presence or absence of pcZF." because this talks about the protein in question and its effects.

0
Private
Assessment
Sandyl 272018-11-14 15:11:23 CSTYou need to be an instructor to view these notes.Unacceptable
Private
Assessment
Sandyl 272018-11-09 12:06:58 CSTYou need to be an instructor to view these notes.Requires Changes
Public
Assessment
DanielRenfro2018-11-06 14:01:10 CST

This annotation has been flagged because it has been challenged since last assessment

Flagged
Private
Assessment
Jrr2018-10-16 18:05:13 CDTYou need to be an instructor to view these notes.Requires Changes
Protein
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Go term
Evidence
Notes