GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

Cacao

Jump to: navigation, search
GO:0010587miRNA catabolic processPMID:18951094IMP: Inferred from Mutant Phenotype P
This annotation made on page: HUMAN:LN28B
By: RazMonk (group Team Gene String) on 2017-02-14 13:56:09 CST.



TeamPoints
Team Gene String5




You must be logged in to challenge this annotation.

Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
Private
Assessment
JimHu2017-04-18 13:47:09 CDTYou need to be an instructor to view these notes.Acceptable
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original
Public
Assessment
DanielRenfro2017-04-18 13:13:05 CDT

This annotation has been flagged because it has been edited since last assessment

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:2000627 positive regulation of miRNA catabolic process PMID:18951094 IMP: Inferred from Mutant Phenotype P "Lin28b was identified via RNA affinity purification of Huh7 cell extracts with pre-let-7a-1"

Fig. 4b shows "in vitro uridylation of pre-let-7a-1 was carried out with purified recombinant Lin28b protein." Fig. 4e shows a quicker decay of target species, pre-let-7a-1, after uridylation by overexpressed human lin28b; up-let-7a-1 is the product of the uridylation of pre-let-7a-1 by lin28b. Called human lin28b.||complete
CACAO 12255

on HUMAN:LN28B
Flagged
Public
Assessment
DanielRenfro2017-04-17 00:00:59 CDT

This annotation has been flagged because it has been edited since last assessment

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:2000627 positive regulation of miRNA catabolic process PMID:18951094 IMP: Inferred from Mutant Phenotype P Fig. 4b shows "in vitro uridylation of pre-let-7a-1 was carried out with purified recombinant Lin28b protein." Fig. 4e shows a quicker decay of target species, pre-let-7a-1, after uridylation by overexpressed human lin28b; up-let-7a-1 is the product of the uridylation of pre-let-7a-1 by lin28b. complete
CACAO 12255
on HUMAN:LN28B
Flagged
Public
Assessment
DanielRenfro2017-02-28 13:45:40 CST

This annotation has been flagged because it has been edited since last assessment

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:2000627 positive regulation of miRNA catabolic process PMID:18951094 IDA: Inferred from Direct Assay P Fig. 4e shows a quicker decay of target species after uridylation by overexpressed human lin28b; pre-let-7a-1 is nonuridylated while up-let-7a-1 is the form uridylated by lin28b. Called Lin28b or collectively as Lin28 in the paper. complete
CACAO 12255
on HUMAN:LN28B
Flagged
Public
Assessment
DanielRenfro2017-02-28 13:44:26 CST

This annotation has been flagged because it has been edited since last assessment

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:2000627 miRNA catabolic process PMID:18951094 IDA: Inferred from Direct Assay P Fig. 4e shows a quicker decay of target species after uridylation by overexpressed human lin28b; pre-let-7a-1 is nonuridylated while up-let-7a-1 is the form uridylated by lin28b. Called Lin28b or collectively as Lin28 in the paper. complete
CACAO 12255
on HUMAN:LN28B
Flagged
Private
Assessment
Suzialeksander2017-02-24 15:42:23 CSTYou need to be an instructor to view these notes.Requires Changes
Publication
Qualifier
Go term
Evidence
With/From
Notes