GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
|GO:0006476||protein deacetylation||PMID:27457971||IMP: Inferred from Mutant Phenotype||P|
|This annotation made on page: HUMAN:SIR6|
By: CSears (group Team Pik-Achoo!) on 2016-10-01 23:20:22 CDT.
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|Entry Type||Challenging User,Group||Time/Date||Challenge Reason||Points/Assessment|
|2016-10-04 20:15:40 CDT|
In my previous challenge, I wrote figure 3A (particularly figure 3C). I meant figure 3 as a whole, instead of figure 3A. Specifically, I would use figure 3C, as stated.
|2016-10-04 20:12:56 CDT|
There is no direct evidence in these figures (4-5) of protein deacetylation by Sirt6. I would use figure 3A (particularly figure 3C) from this paper to show the deacetylase activty of Sirt6 on Fox01. Figure 3C shows that immunoprecipitation of acetylated-Fox01 is decreased when Sirt6 is added. This means that the total amount of acetylated Fox01 is reduced when Sirt6 is present, showing that Sirt6 is involved in protein deacetylation.
|Suzialeksander||2016-11-30 15:26:49 CST||You need to be an instructor to view these notes.||Updated by Instructor|
|Suzialeksander||2016-10-11 15:24:58 CDT||You need to be an instructor to view these notes.||Requires Changes|
✔ Go term
|DanielRenfro||2016-10-04 20:15:40 CDT|
This annotation has been flagged because it has been challenged since last assessment
|Sandyl 27||2016-10-04 20:15:18 CDT||You need to be an instructor to view these notes.||Requires Changes|
✔ Go term