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GO:0016787hydrolase activityPMID:17878153IDA: Inferred from Direct Assay F
This annotation made on page: BPT4:UVSW
By: Powellme (group Team TRUMP2016) on 2016-05-02 10:29:07 CDT.



TeamPoints
Team TRUMP20160




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
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Suzialeksander2016-05-23 15:48:32 CDTYou need to be an instructor to view these notes.Unacceptable
Evidence
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AAJohnson2016-05-04 10:40:59 CDT

Figure 2 doesn't show the molecule has hydrolase activity. A more general GO term for helicase would be appropriate. http://amigo.geneontology.org/amigo/search/ontology?q=helicase

The evidence code should be ISS, not IDA, since it is a figure of secondary structure mapped into the primary amino acid sequence. [If the crystallization experiment (Figure 1) was used, IDA might be appropriate, with Figure 2 as further support for conservation of secondary structure among monomeric helicases.]

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