STRPZ:MUTL

Species (Taxon ID)	Streptococcus pyogenes serotype M49 (strain NZ131). (471876)
Gene Name(s)	mutL (ECO:0000255 with HAMAP-Rule:MF_00149)
Protein Name(s)	DNA mismatch repair protein MutL (ECO:0000255 with HAMAP-Rule:MF_00149)
External Links
UniProt	B5XJ09
EMBL	CP000829
RefSeq	WP_009880530.1
ProteinModelPortal	B5XJ09
EnsemblBacteria	ACI62008
KEGG	soz:Spy49_1758c
PATRIC	19758662
HOGENOM	HOG000256552
KO	K03572
OMA	QFLFINN
OrthoDB	EOG6P8TMH
Proteomes	UP000001039
GO	GO:0005524 GO:0030983 GO:0006298
Gene3D	3.30.230.10 3.30.565.10
HAMAP	MF_00149
InterPro	IPR013507 IPR014762 IPR002099 IPR020667 IPR003594 IPR014790 IPR020568 IPR014721
Pfam	PF01119 PF02518 PF08676
SMART	SM00387 SM00853
SUPFAM	SSF54211 SSF55874
TIGRFAMs	TIGR00585
PROSITE	PS00058

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0032423	regulation of mismatch repair	PMID:26701803	ECO:0000315			P		Figure 1 shows that when MutL is disrupted, the mutations in the cells increase.	complete CACAO 11295
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002099 InterPro:IPR013507 InterPro:IPR014790	F		Seeded From UniProt	complete
involved_in	GO:0006298	mismatch repair	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002099 InterPro:IPR013507 InterPro:IPR014790 InterPro:IPR020667 InterPro:IPR038973	P		Seeded From UniProt	complete
enables	GO:0016887	ATPase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR038973	F		Seeded From UniProt	complete
enables	GO:0030983	mismatched DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002099 InterPro:IPR013507	F		Seeded From UniProt	complete
part_of	GO:0032300	mismatch repair complex	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR038973	C		Seeded From UniProt	complete
involved_in	GO:0006298	mismatch repair	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000001258	P		Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0227	P		Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0234	P		Seeded From UniProt	complete
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References

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