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STRPY:W0S3I8

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Species (Taxon ID) Streptococcus pyogenes. (1314)
Gene Name(s) rocA (ECO:0000313 with EMBL:BAO25591.1)
Protein Name(s) Histidine kinase (ECO:0000313 with EMBL:CKH04991.1)

RocA protein (ECO:0000313 with EMBL:BAO25591.1) Sensory transduction protein kinase (ECO:0000313 with EMBL:BAO25592.1)

External Links
UniProt W0S3I8
EMBL AB737849
AB737850
LN831034
RefSeq WP_010922531.1
STRING 160490.SPy_1605
eggNOG COG2972
GO GO:0016021
GO:0016301
InterPro IPR032834
Pfam PF14501

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0045892

negative regulation of transcription, DNA-templated

PMID:27349341[1]

ECO:0000315

P

Figure 3B and 3C: Streptococcus pyogenes serotype M1(MGAS5005) with mutation in rocA promoter showed increased transcription of nga and sda1 virulence genes

complete
CACAO 12353

part_of

GO:0016020

membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Ikebe, T et al. (2016) Spontaneous mutations in Streptococcus pyogenes isolates from streptococcal toxic shock syndrome patients play roles in virulence. Sci Rep 6 28761 PubMed GONUTS page