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STRPY:Q4VYB9

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Species (Taxon ID) Streptococcus pyogenes. (1314)
Gene Name(s) erm(B) (ECO:0000313 with EMBL:CAI99373.1)
Protein Name(s) Erm(B) (ECO:0000313 with EMBL:CAL69877.1)

RRNA adenine N-6-methyltransferase (ECO:0000313 with EMBL:CAI99373.1) rRNA methylase (ECO:0000313 with EMBL:CCH26391.1)

External Links
UniProt Q4VYB9
EMBL AJ972606
AM411377
HE802677
ProteinModelPortal Q4VYB9
SMR Q4VYB9
GO GO:0003723
GO:0000179
Gene3D 1.10.8.100
3.40.50.150
InterPro IPR001737
IPR023165
IPR020596
IPR020598
IPR029063
PANTHER PTHR11727
Pfam PF00398
SMART SM00650
SUPFAM SSF53335
PROSITE PS01131
PS51689

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0010467

gene expression

PMID:15386111[1]

ECO:0000315

P

The characteristics of ermB strains within the conclusion section states that erthromycin and josamycin resistance is present within the gene. The use of the triple disk sensitivity assay was the way that they could determine what ermB was resistant to.

complete
CACAO 11351

involved_in

GO:0000154

rRNA modification

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR020596
InterPro:IPR020598

P

Seeded From UniProt

complete

enables

GO:0000179

rRNA (adenine-N6,N6-)-dimethyltransferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR020596
InterPro:IPR020598

F

Seeded From UniProt

complete

enables

GO:0008649

rRNA methyltransferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR020596
InterPro:IPR020598

F

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0694

F

Seeded From UniProt

complete

enables

GO:0008168

methyltransferase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0489

F

Seeded From UniProt

complete

involved_in

GO:0032259

methylation

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0489

P

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

involved_in

GO:0031167

rRNA methylation

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000413377

P

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000413377

F

Seeded From UniProt

complete

enables

GO:0000179

rRNA (adenine-N6,N6-)-dimethyltransferase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000413377

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Champney, WS et al. (2004) An examination of the differential sensitivity to ketolide antibiotics in ermB strains of Streptococcus pyogenes and Streptococcus pneumoniae. Curr. Microbiol. 49 239-47 PubMed GONUTS page