STRPY:MEFA

Species (Taxon ID)	Streptococcus pyogenes. (1314)
Gene Name(s)	mefA (ECO:0000312 with EMBL:AAL73129.1)
Protein Name(s)	Macrolide efflux protein A (ECO:0000312 with EMBL:AAL73129.1)
External Links
UniProt	P95827
EMBL	U70055 AF227521 AY657002
ProteinModelPortal	P95827
TCDB	2.A.1.21.1
KEGG	ag:AAC44785
KO	K08217
GO	GO:0016021 GO:0005886 GO:0015307 GO:0046677
InterPro	IPR004751 IPR011701 IPR020846
Pfam	PF07690
SUPFAM	SSF103473
TIGRFAMs	TIGR00900
PROSITE	PS50850

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0010467	gene expression	PMID:21502613	ECO:0000315			P		Table 1 shows the strains and their resistance genes. The conclusion paragraph states that the mefA are apart of the resistant genes and similar to those already identified with S. pyogenes or S. pneumoniae.	complete CACAO 11350
involved_in	GO:0046618	drug export	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0015307	P		Seeded From UniProt	complete
enables	GO:0015307	drug:proton antiporter activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004751	F		Seeded From UniProt	complete
involved_in	GO:0015893	drug transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004751	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011701	C		Seeded From UniProt	complete
involved_in	GO:0055085	transmembrane transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011701	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
involved_in	GO:0046677	response to antibiotic	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0046	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
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References

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