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STRPN:A7KT31

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Species (Taxon ID) Streptococcus pneumoniae. (1313)
Gene Name(s) rrgA
Protein Name(s) Ancillary pilus subunit
External Links
UniProt A7KT31
EMBL EF560626
EF560629
EF560630
ProteinModelPortal A7KT31
InterPro IPR008454
IPR008970
IPR002035
Pfam PF05738
PF00092
SMART SM00327
SUPFAM SSF49478
PROSITE PS50234

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0086080

protein binding involved in heterotypic cell-cell adhesion

PMID:17850254[1]

ECO:0000315

F

Figure 5 RrgA is involved in pilus-mediated colonization of the upper respiratory tract in mice. The mice were infected with T4 phage with rrgA and rrgB/rrgC deletions respectively. Seven days after infection, Mice infected with T4 rrgA deletion phage had significantly less bacteria in the nasopharynx than mice infected with T4 rrgB/rrgC deletion phage. This demonstrates that rrgA is important for pilli assembly and strong cell wall adhesion.

complete
CACAO 4075

part_of

GO:0016020

membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Nelson, AL et al. (2007) RrgA is a pilus-associated adhesin in Streptococcus pneumoniae. Mol. Microbiol. 66 329-40 PubMed GONUTS page