STRP1:Q9A174

Species (Taxon ID)	Streptococcus pyogenes serotype M1. (301447)
Gene Name(s)	spyA (ECO:0000313 with EMBL:AAZ50969.1)
Protein Name(s)	C3 family ADP-ribosyltransferase (ECO:0000313 with EMBL:AAZ50969.1) Uncharacterized protein (ECO:0000313 with EMBL:AAK33450.1)
External Links
UniProt	Q9A174
EMBL	AE004092 CP000017
RefSeq	NP_268729.1 YP_281714.1
ProteinModelPortal	Q9A174
EnsemblBacteria	AAK33450 AAZ50969
GeneID	3572562 900678
KEGG	spy:SPy_0428 spz:M5005_Spy_0351
PATRIC	19714589
HOGENOM	HOG000235564
KO	K11044
OMA	VEVRICV
OrthoDB	EOG6VTK0T
BioCyc	SPYO160490:GJ81-363-MONOMER SPYO293653:GHFC-406-MONOMER
Proteomes	UP000000750 UP000002702
GO	GO:0005576 GO:0016757 GO:0016763 GO:0009405 GO:0006471
InterPro	IPR003540 IPR016678
Pfam	PF03496
PIRSF	PIRSF016951

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0016757	transferase activity, transferring glycosyl groups	PMID:15458407	ECO:0000315			F		Mutant phenotype was inferred based on Figure 4, in which SpyA was assayed for the ability to ADP-ribosylate arginine. As shown, there was labelled precipitated material when SpyA was incubated with poly-l-arginine and only limited precipitated radioactive material with the active site mutant SpyA-E187A.	complete CACAO 4544
enables	GO:0016757	transferase activity, transferring glycosyl groups	PMID:15458407	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003540	C		Seeded From UniProt	complete
involved_in	GO:0006471	protein ADP-ribosylation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016678	P		Seeded From UniProt	complete
involved_in	GO:0009405	pathogenesis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003540	P		Seeded From UniProt	complete
enables	GO:0016763	transferase activity, transferring pentosyl groups	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016678	F		Seeded From UniProt	complete
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References

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