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STRCO:METK
Contents
| Species (Taxon ID) | Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145). (100226) | |
| Gene Name(s) | metK (ECO:0000255 with HAMAP-Rule:MF_00086) | |
| Protein Name(s) | S-adenosylmethionine synthase (ECO:0000255 with HAMAP-Rule:MF_00086)
AdoMet synthase (ECO:0000255 with HAMAP-Rule:MF_00086) MAT (ECO:0000255 with HAMAP-Rule:MF_00086) Methionine adenosyltransferase (ECO:0000255 with HAMAP-Rule:MF_00086) | |
| External Links | ||
| UniProt | Q9L0Y3 | |
| EMBL | AL939109 | |
| RefSeq | NP_625757.1 | |
| ProteinModelPortal | Q9L0Y3 | |
| SMR | Q9L0Y3 | |
| STRING | 100226.SCO1476 | |
| PRIDE | Q9L0Y3 | |
| EnsemblBacteria | CAB76898 | |
| GeneID | 1096902 | |
| KEGG | sco:SCO1476 | |
| PATRIC | 23732528 | |
| eggNOG | COG0192 | |
| HOGENOM | HOG000245710 | |
| InParanoid | Q9L0Y3 | |
| KO | K00789 | |
| OMA | IGEQSPD | |
| OrthoDB | EOG68WR6M | |
| PhylomeDB | Q9L0Y3 | |
| UniPathway | UPA00315 | |
| Proteomes | UP000001973 | |
| GO | GO:0005737 GO:0005524 GO:0000287 GO:0004478 GO:0006730 GO:0006556 | |
| HAMAP | MF_00086 | |
| InterPro | IPR022631 IPR022630 IPR022629 IPR022628 IPR002133 IPR022636 | |
| PANTHER | PTHR11964 | |
| Pfam | PF02773 PF02772 PF00438 | |
| PIRSF | PIRSF000497 | |
| SUPFAM | SSF55973 | |
| TIGRFAMs | TIGR01034 | |
| PROSITE | PS00376 PS00377 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0006556 |
S-adenosylmethionine biosynthetic process |
ECO:0000315 |
P |
Table 1: as expected, the level of intracellular SAM in KO-179 was found to be markedly elevated relative to the wild-type strain. |
complete | |||||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10589 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004478 |
methionine adenosyltransferase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10589 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004478 |
methionine adenosyltransferase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR002133 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006556 |
S-adenosylmethionine biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR002133 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004478 |
methionine adenosyltransferase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004478 |
methionine adenosyltransferase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000076340 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0000287 |
magnesium ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000076340 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000076340 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000076340 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006730 |
one-carbon metabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000076340 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006730 |
one-carbon metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006556 |
S-adenosylmethionine biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00315 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Okamoto, S et al. (2003) Enhanced expression of S-adenosylmethionine synthetase causes overproduction of actinorhodin in Streptomyces coelicolor A3(2). J. Bacteriol. 185 601-9 PubMed GONUTS page
- ↑ 2.0 2.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
