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STAAU:MGRA

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Species (Taxon ID) Staphylococcus aureus. (1280)
Gene Name(s) mgrA (synonyms: mgr)
Protein Name(s) HTH-type transcriptional regulator MgrA

Regulator of autolytic activity

External Links
UniProt P0C1S0
EMBL AY293568
RefSeq WP_001283444.1
PDB 2BV6
PDBsum 2BV6
ProteinModelPortal P0C1S0
SMR P0C1S0
BindingDB P0C1S0
ChEMBL CHEMBL2331056
eggNOG COG1846
EvolutionaryTrace P0C1S0
GO GO:0005737
GO:0003677
GO:0003700
GO:0009405
GO:0006351
Gene3D 1.10.10.10
InterPro IPR000835
IPR023187
IPR011991
Pfam PF01047
SMART SM00347
PROSITE PS01117
PS50995

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0010629

negative regulation of gene expression

PMID:15774883[1]

ECO:0000314

P

Figure 4. mgrA directly regulates norB and nor A and indirectly negatively regulates expression of tet38.

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000835

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000835

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

involved_in

GO:0009405

pathogenesis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0843

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Truong-Bolduc, QC et al. (2005) MgrA is a multiple regulator of two new efflux pumps in Staphylococcus aureus. J. Bacteriol. 187 2395-405 PubMed GONUTS page