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STAAU:MECI
Contents
Species (Taxon ID) | Staphylococcus aureus. (1280) | |
Gene Name(s) | mecI | |
Protein Name(s) | Methicillin resistance regulatory protein MecI | |
External Links | ||
UniProt | P68262 | |
EMBL | L14020 | |
ProteinModelPortal | P68262 | |
SMR | P68262 | |
GO | GO:0005737 GO:0003677 GO:0045892 GO:0046677 GO:0006351 | |
Gene3D | 1.10.10.10 | |
InterPro | IPR005650 IPR011991 | |
Pfam | PF03965 | |
PIRSF | PIRSF019455 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0006355 |
regulation of transcription, DNA-dependent |
ECO:0000314 |
P |
Table 2 shows that in cells transformed with mecI, the beta-galactosidase activity of mecA-lacZ transcriptional fusion can be induced with the presence of CBAP. Furthermore, it is shown in Fig. 2 that mecI binds to a region of DNA between the mecA and mecR1 genes and protects it from DNase. |
complete | |||||
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0045892 |
negative regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0046677 |
response to antibiotic |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Sharma, VK et al. (1998) Interaction of native and mutant MecI repressors with sequences that regulate mecA, the gene encoding penicillin binding protein 2a in methicillin-resistant staphylococci. J. Bacteriol. 180 2160-6 PubMed GONUTS page