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STAAU:BLAI

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Species (Taxon ID) Staphylococcus aureus. (1280)
Gene Name(s) blaI (synonyms: penI)
Protein Name(s) Penicillinase repressor

Beta-lactamase repressor protein Regulatory protein BlaI

External Links
UniProt P0A042
EMBL X52734
M62650
M92376
PIR S11782
RefSeq NP_878025.1
YP_003329486.1
YP_006937604.1
YP_006937749.1
YP_006938265.1
YP_006938772.1
YP_008709797.1
PDB 1SD4
1XSD
PDBsum 1SD4
1XSD
ProteinModelPortal P0A042
SMR P0A042
GeneID 13874752
13874901
13875432
13875953
17363237
2598289
8655738
EvolutionaryTrace P0A042
GO GO:0005737
GO:0003677
GO:0045892
GO:0010468
GO:0046677
GO:0006351
Gene3D 1.10.10.10
InterPro IPR005650
IPR011991
Pfam PF03965
PIRSF PIRSF019455

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0010468

regulation of gene expression

PMID:8517704[1]

ECO:0000314

P

Fig. 2 shows that expression PBP 2a and beta-lactamase was repressed in cells transformed with blaI, but PBP 2a and beta-lactamase were expressed constitutively in untransformed cells. Furthermore, expression in transformed cells could be induced.

complete
CACAO 4680

GO:0008800

beta-lactamase activity

PMID:26796298[2]

ECO:0000314

F

Table 1. Distribution of various virulence, regulatory and toxin genes.

complete
CACAO 11281

involved_in

GO:0010468

regulation of gene expression

PMID:8517704[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005650

F

Seeded From UniProt

complete

involved_in

GO:0045892

negative regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005650

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

involved_in

GO:0046677

response to antibiotic

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0046

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Hackbarth, CJ & Chambers, HF (1993) blaI and blaR1 regulate beta-lactamase and PBP 2a production in methicillin-resistant Staphylococcus aureus. Antimicrob. Agents Chemother. 37 1144-9 PubMed GONUTS page
  2. Sarkar, A et al. (2016) Antimicrobial resistance and virulence markers in methicillin sensitive Staphylococcus aureus isolates associated with nasal colonization. Microb. Pathog. 93 8-12 PubMed GONUTS page