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STAAU:BLAI
Contents
Species (Taxon ID) | Staphylococcus aureus. (1280) | |
Gene Name(s) | blaI (synonyms: penI) | |
Protein Name(s) | Penicillinase repressor
Beta-lactamase repressor protein Regulatory protein BlaI | |
External Links | ||
UniProt | P0A042 | |
EMBL | X52734 M62650 M92376 | |
PIR | S11782 | |
RefSeq | NP_878025.1 YP_003329486.1 YP_006937604.1 YP_006937749.1 YP_006938265.1 YP_006938772.1 YP_008709797.1 | |
PDB | 1SD4 1XSD | |
PDBsum | 1SD4 1XSD | |
ProteinModelPortal | P0A042 | |
SMR | P0A042 | |
GeneID | 13874752 13874901 13875432 13875953 17363237 2598289 8655738 | |
EvolutionaryTrace | P0A042 | |
GO | GO:0005737 GO:0003677 GO:0045892 GO:0010468 GO:0046677 GO:0006351 | |
Gene3D | 1.10.10.10 | |
InterPro | IPR005650 IPR011991 | |
Pfam | PF03965 | |
PIRSF | PIRSF019455 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0010468 |
regulation of gene expression |
ECO:0000314 |
P |
Fig. 2 shows that expression PBP 2a and beta-lactamase was repressed in cells transformed with blaI, but PBP 2a and beta-lactamase were expressed constitutively in untransformed cells. Furthermore, expression in transformed cells could be induced. |
complete | |||||
GO:0008800 |
beta-lactamase activity |
ECO:0000314 |
F |
Table 1. Distribution of various virulence, regulatory and toxin genes. |
complete | |||||
involved_in |
GO:0010468 |
regulation of gene expression |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0045892 |
negative regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0046677 |
response to antibiotic |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Hackbarth, CJ & Chambers, HF (1993) blaI and blaR1 regulate beta-lactamase and PBP 2a production in methicillin-resistant Staphylococcus aureus. Antimicrob. Agents Chemother. 37 1144-9 PubMed GONUTS page
- ↑ Sarkar, A et al. (2016) Antimicrobial resistance and virulence markers in methicillin sensitive Staphylococcus aureus isolates associated with nasal colonization. Microb. Pathog. 93 8-12 PubMed GONUTS page