STAAU:B0YLX3

Species (Taxon ID)	Staphylococcus aureus. (1280)
Gene Name(s)	No Information Provided.
Protein Name(s)	PVL toxin (ECO:0000313 with EMBL:ABU54603.1)
External Links
UniProt	B0YLX3
EMBL	EF571672 EF571673 EF571674 EF571675 EF571685 EF571690 EF571692 EF571695 EF571724 EF571725 EF571762 EF571765 EF571774 EF571790 EF571791 EF571792 EF571793 EF571794 EF571795 EF571796 EF571797 EF571798 EF571799 EF571800 EF571801 EF571803 EF571804 EF571805 EF571806 EF571807 EF571808 EF571809 EF571810 EF571811 EF571812 EF571813 EF571814 EF571815 EF571816 EF571817 EF571818 EF571819 EF571820 EF571821 EF571822 EF571823 EF571824 EF571825 EF571826 EF571827 EF571828 EF571830 EF571831 EF571832 EF571833 EF571834 EF571837 EF571838 EF571839 EF571840 EF571841
GO	GO:0005576 GO:0051715 GO:0009405
Gene3D	2.70.240.10
InterPro	IPR003963 IPR016183
Pfam	PF07968
PRINTS	PR01468
SUPFAM	SSF56959
TIGRFAMs	TIGR01002

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0009405	pathogenesis	PMID:24847020	ECO:0000314			P		Figure 2A and 2B. Images show macrophages and neutrophils being killed by PVL. Characteristic membrane halos and expansion of cellular nuclei are seen, along with increased permeability to ethidium bromide (indicator of pore formation and membrane damage)	complete CACAO 11181
	GO:0009405	pathogenesis	PMID:26091719	ECO:0000314			P		Figure 1A. Pore formation in freshly isolated neutrophils from different mammalian species after incubation with PVL shows differential species-specific cytotoxicity of PVL. PVL is active only toward human and rabbit neutrophils, but not toward neutrophils from macaque, cow, and mouse	complete CACAO 11182
part_of	GO:0005576	extracellular region	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003963 InterPro:IPR016183	C		Seeded From UniProt	complete
involved_in	GO:0009405	pathogenesis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003963	P		Seeded From UniProt	complete
involved_in	GO:0051715	cytolysis in other organism	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016183	P		Seeded From UniProt	complete
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References

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