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STAAE:ESXB
Contents
| Species (Taxon ID) | Staphylococcus aureus (strain Newman). (426430) | |
| Gene Name(s) | esxB | |
| Protein Name(s) | Virulence factor EsxB | |
| External Links | ||
| UniProt | P0C047 | |
| EMBL | AP009351 | |
| RefSeq | YP_001331259.1 | |
| STRING | 426430.NWMN_0225 | |
| EnsemblBacteria | BAF66497 | |
| GeneID | 5330068 | |
| KEGG | sae:NWMN_0225 | |
| PATRIC | 19583796 | |
| eggNOG | NOG76543 | |
| HOGENOM | HOG000279764 | |
| OrthoDB | EOG647V1Z | |
| BioCyc | SAUR426430:GIXC-227-MONOMER | |
| Proteomes | UP000006386 | |
| GO | GO:0005576 GO:0009405 | |
| InterPro | IPR010310 | |
| Pfam | PF06013 | |
| SUPFAM | SSF140453 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
Contributes to |
GO:0009405 |
pathogenesis |
ECO:0000315 |
P |
Fig 5 indicates that mutations in the secretion of EsxB cause a 2- to 4-log reduction in the ability of these mutant staphylococci to establish abscesses in infected mice--EsxA and EsxB represent an important virulence strategy in S. aureus. |
complete | ||||
|
involved_in |
GO:0009405 |
pathogenesis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Burts, ML et al. (2005) EsxA and EsxB are secreted by an ESAT-6-like system that is required for the pathogenesis of Staphylococcus aureus infections. Proc. Natl. Acad. Sci. U.S.A. 102 1169-74 PubMed GONUTS page
