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STAAE:CLFA

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Species (Taxon ID) Staphylococcus aureus (strain Newman). (426430)
Gene Name(s) clfA
Protein Name(s) Clumping factor A

Fibrinogen receptor A Fibrinogen-binding protein A

External Links
UniProt Q53653
EMBL Z18852
AP009351
PIR S41539
RefSeq YP_001331790.1
PDB 1N67
PDBsum 1N67
ProteinModelPortal Q53653
SMR Q53653
STRING 426430.NWMN_0756
EnsemblBacteria BAF67028
GeneID 5330438
KEGG sae:NWMN_0756
PATRIC 19584983
eggNOG NOG12793
HOGENOM HOG000022927
KO K14201
OMA DASENSM
OrthoDB EOG6RNQ8T
BioCyc SAUR426430:GIXC-776-MONOMER
EvolutionaryTrace Q53653
PRO PR:Q53653
Proteomes UP000006386
GO GO:0005618
GO:0005576
GO:0016020
GO:0007155
GO:0009405
Gene3D 2.60.40.1280
2.60.40.1290
InterPro IPR011266
IPR008966
IPR011252
IPR019931
IPR005877
Pfam PF10425
PF04650
SUPFAM SSF49401
TIGRFAMs TIGR01167
TIGR01168
PROSITE PS50847

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0009405

pathogenesis

PMID:22028651[1]

ECO:0000315

P

Fig. 1 Clumping Factor A has shown to be the most important of a three gene system: clfA, vwb, and coa. Mutations to clfA severely impaired agglutination.

complete
CACAO 9596

involved_in

GO:0009405

pathogenesis

PMID:22028651[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005618

cell wall

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011266

C

Seeded From UniProt

complete

involved_in

GO:0007155

cell adhesion

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011252
InterPro:IPR011266

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005877

C

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964

C

Seeded From UniProt

complete

involved_in

GO:0009405

pathogenesis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0843

P

Seeded From UniProt

complete

part_of

GO:0005618

cell wall

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0134
UniProtKB-SubCell:SL-0041

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 McAdow, M et al. (2011) Preventing Staphylococcus aureus sepsis through the inhibition of its agglutination in blood. PLoS Pathog. 7 e1002307 PubMed GONUTS page