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STAAC:PFLA

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Species (Taxon ID) Staphylococcus aureus (strain COL). (93062)
Gene Name(s) pflA
Protein Name(s) Pyruvate formate-lyase-activating enzyme

PFL-activating enzyme

External Links
UniProt Q5HJF3
EMBL CP000046
RefSeq YP_185104.1
ProteinModelPortal Q5HJF3
SMR Q5HJF3
STRING 93062.SACOL0205
PRIDE Q5HJF3
EnsemblBacteria AAW37501
GeneID 3236775
KEGG sac:SACOL0205
PATRIC 19526676
eggNOG COG1180
HOGENOM HOG000011458
KO K04069
OMA RFVLFMQ
OrthoDB EOG64FKHC
BioCyc SAUR93062:GCEP-200-MONOMER
Proteomes UP000000530
GO GO:0005737
GO:0051539
GO:0043365
GO:0046872
GO:0006006
InterPro IPR012838
IPR001989
IPR007197
Pfam PF04055
TIGRFAMs TIGR02493
PROSITE PS01087

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0016491

oxidoreductase activity

PMID:21169491[1]

ECO:0000315

F

FIG. 2. Formate accumulation in the TSB culture supernatant of anaerobically grown cells. TABLE 4. Accumulated fermentation products, glucose consumption, pH of culture supernatant, and OD578 after anaerobic growth in IMDMa

complete

GO:0015943

formate biosynthetic process

PMID:21169491[1]

ECO:0000315

P

FIG. 4. Glucose consumption and formate accumulation in culture supernatants as detected by 1H-NMR.

complete

enables

GO:0003824

catalytic activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR007197
InterPro:IPR013785

F

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001989
InterPro:IPR012839

F

Seeded From UniProt

complete

enables

GO:0043365

[formate-C-acetyltransferase]-activating enzyme activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012838

F

Seeded From UniProt

complete

enables

GO:0051536

iron-sulfur cluster binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR007197

F

Seeded From UniProt

complete

enables

GO:0051539

4 iron, 4 sulfur cluster binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001989

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001989
InterPro:IPR012838
InterPro:IPR012839

P

Seeded From UniProt

complete

enables

GO:0043365

[formate-C-acetyltransferase]-activating enzyme activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:1.97.1.4

F

Seeded From UniProt

complete

involved_in

GO:0006006

glucose metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0313

P

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

P

Seeded From UniProt

complete

enables

GO:0051536

iron-sulfur cluster binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0411

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

complete

involved_in

GO:0005975

carbohydrate metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0119

P

Seeded From UniProt

complete

enables

GO:0051539

4 iron, 4 sulfur cluster binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0004

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Leibig, M et al. (2011) Pyruvate formate lyase acts as a formate supplier for metabolic processes during anaerobiosis in Staphylococcus aureus. J. Bacteriol. 193 952-62 PubMed GONUTS page