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STAA8:LRGB

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Species (Taxon ID) Staphylococcus aureus (strain NCTC 8325). (93061)
Gene Name(s) lrgB
Protein Name(s) Antiholin-like protein LrgB
External Links
UniProt P60643
EMBL U52961
CP000253
RefSeq WP_000607067.1
YP_498828.1
STRING 93061.SAOUHSC_00233
TCDB 2.A.122.1.3
EnsemblBacteria ABD29408
GeneID 28379420
3920308
KEGG sao:SAOUHSC_00233
PATRIC 19578076
eggNOG ENOG41067MG
COG1346
HOGENOM HOG000253604
KO K05339
OMA WQIMSSI
Proteomes UP000008816
GO GO:0016021
GO:0005886
GO:0019835
HAMAP MF_01142
InterPro IPR024891
IPR007300
PANTHER PTHR30249
Pfam PF04172

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005886

plasma membrane

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

Seeded From UniProt

GO:0005886

plasma membrane

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

GO:0016020

membrane

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

Seeded From UniProt

GO:0016021

integral component of membrane

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

Seeded From UniProt

GO:0019835

cytolysis

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0204

P

Seeded From UniProt

GO:1900231

regulation of single-species biofilm formation on inanimate substrate

PMID:26406329[1]

IMP: Inferred from Mutant Phenotype

P

In Figure 1A it is shown that when knocking out the gene LrgB, biofilm production on an inert polystyrene surface greatly increased, showing that LrgB has a role in the regulation of biofilm production.

complete
CACAO 12667

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Beltrame, CO et al. (2015) Inactivation of the Autolysis-Related Genes lrgB and yycI in Staphylococcus aureus Increases Cell Lysis-Dependent eDNA Release and Enhances Biofilm Development In Vitro and In Vivo. PLoS ONE 10 e0138924 PubMed GONUTS page