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STAA8:LACR

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Species (Taxon ID) Staphylococcus aureus (strain NCTC 8325). (93061)
Gene Name(s) lacR
Protein Name(s) Lactose phosphotransferase system repressor
External Links
UniProt P0A0Q0
EMBL M32103
CP000253
PIR A44506
RefSeq YP_500923.1
ProteinModelPortal P0A0Q0
STRING 93061.SAOUHSC_02456
EnsemblBacteria ABD31476
GeneID 3919019
KEGG sao:SAOUHSC_02456
PATRIC 19582218
eggNOG COG1349
HOGENOM HOG000224683
KO K02530
OrthoDB EOG6XSZXW
BioCyc SAUR93061:GIWJ-2391-MONOMER
Proteomes UP000008816
GO GO:0005622
GO:0003677
GO:0003700
GO:0005988
GO:0006355
GO:0006351
Gene3D 1.10.10.10
InterPro IPR014036
IPR001034
IPR018356
IPR011991
Pfam PF00455
PF08220
PRINTS PR00037
SMART SM00420
PROSITE PS00894
PS51000

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0006355

regulation of transcription, DNA-dependent

PMID:2163387[1]

ECO:0000315

P

Fig. 6 shows that the introduction of the frameshift mutation causes premature termination of the lacR protein product resulting in a loss of repressor activity.

complete
CACAO 3804

involved_in

GO:0006355

regulation of transcription, DNA-templated

PMID:2163387[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001034
InterPro:IPR018356

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001034
InterPro:IPR018356

P

Seeded From UniProt

complete

involved_in

GO:0005988

lactose metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0423

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Oskouian, B & Stewart, GC (1990) Repression and catabolite repression of the lactose operon of Staphylococcus aureus. J. Bacteriol. 172 3804-12 PubMed GONUTS page