STAA8:HLA

Species (Taxon ID)	Staphylococcus aureus (strain NCTC 8325). (93061)
Gene Name(s)	hly (synonyms: hla)
Protein Name(s)	Alpha-hemolysin Alpha-HL Alpha-toxin
External Links
UniProt	Q2G1X0
EMBL	CP000253
RefSeq	YP_499665.1
PDB	4U6V
PDBsum	4U6V
ProteinModelPortal	Q2G1X0
SMR	Q2G1X0
STRING	93061.SAOUHSC_01121
EnsemblBacteria	ABD30233
GeneID	3920722
KEGG	sao:SAOUHSC_01121
PATRIC	19579739
eggNOG	NOG41533
HOGENOM	HOG000279992
KO	K11032
OMA	AYHTEAE
OrthoDB	EOG6N67ZC
BioCyc	SAUR93061:GIWJ-1078-MONOMER
PRO	PR:Q2G1X0
Proteomes	UP000008816
GO	GO:0005576 GO:0044179 GO:0009405
Gene3D	2.70.240.10
InterPro	IPR005831 IPR003963 IPR016183
Pfam	PF07968
PRINTS	PR01468
SUPFAM	SSF56959
TIGRFAMs	TIGR01002
PROSITE	PS00274

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0009405	pathogenesis	PMID:3679545	ECO:0000315			P		Table 4: Shows the effect of Hly- and Hly+ mutant genotypes on the size of skin lesions in rats. This was tested with varying doses of inoculum.	complete CACAO 8854
involved_in	GO:0009405	pathogenesis	PMID:3679545	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003963 InterPro:IPR005831 InterPro:IPR016183	C		Seeded From UniProt	complete
involved_in	GO:0009405	pathogenesis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003963	P		Seeded From UniProt	complete
involved_in	GO:0051715	cytolysis in other organism	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016183	P		Seeded From UniProt	complete
involved_in	GO:0044179	hemolysis in other organism	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0354	P		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
enables	GO:0090729	toxin activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0800	F		Seeded From UniProt	complete
involved_in	GO:0009405	pathogenesis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0843	P		Seeded From UniProt	complete
involved_in	GO:0019835	cytolysis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0204	P		Seeded From UniProt	complete
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References

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