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STAA3:SARA

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Species (Taxon ID) Staphylococcus aureus (strain USA300). (367830)
Gene Name(s) sarA
Protein Name(s) Transcriptional regulator SarA

Staphylococcal accessory regulator A

External Links
UniProt Q2FJ20
EMBL CP000255
ProteinModelPortal Q2FJ20
SMR Q2FJ20
EnsemblBacteria ABD22859
KEGG saa:SAUSA300_0605
PATRIC 19590497
HOGENOM HOG000279851
OMA NENDERT
OrthoDB EOG6FV869
BioCyc SAUR451515:GH3C-605-MONOMER
PRO PR:Q2FJ20
Proteomes UP000001939
GO GO:0005737
GO:0003677
GO:0046872
GO:0009405
GO:0006355
GO:0006351
Gene3D 1.10.10.10
InterPro IPR010166
IPR011991
SUPFAM SSF46785
TIGRFAMs TIGR01889

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010166

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

GO:0045862

proteolysis

PMID:25257373[1]

ECO:0000315

P

Figure 3 shows the impact of mutating individual protease genes or operons in both the WT and sarA mutant in terms of proteolytic activity.

complete
CACAO 11383

involved_in

GO:0009405

pathogenesis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0843

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

GO:0090609

single-species submerged biofilm formation

PMID:25257373[1]

ECO:0000315

P

Figure 6 shows the impact of mutating individual protease genes or operons in both the WT and sarA mutant in terms of biofilm formation.

complete
CACAO 11387

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Loughran, AJ et al. (2014) Impact of individual extracellular proteases on Staphylococcus aureus biofilm formation in diverse clinical isolates and their isogenic sarA mutants. Microbiologyopen 3 897-909 PubMed GONUTS page