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|Species (Taxon ID)||Shigella flexneri. (623)|
|Gene Name(s)||ospC3 (ECO:0000313 with EMBL:CAC05795.1)|
|Protein Name(s)||Uncharacterized protein ospC3 (ECO:0000313 with EMBL:CAC05795.1)|
|Qualifier||GO ID||GO term name||Reference||ECO ID||ECO term name||with/from||Aspect||Extension||Notes||Status|
negative regulation by symbiont of host defense-related programmed cell death
Organism: Shigella Flexneri protein: OspC3 Supplementary figure 1A shows that "...one of the mutants lacking ospC3 (ΔospC3) greatly enhanced cell death at 2 and 4 hr compared to the other effector mutants and YSH6000 (wild-type [WT] Shigella) (Figure S1A), suggesting that OspC3 suppresses the cell death response to Shigella infection." Host: human skin cells
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