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SHIDY:STXA

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Species (Taxon ID) Shigella dysenteriae. (622)
Gene Name(s) stxA
Protein Name(s) Shiga toxin subunit A
External Links
UniProt Q9FBI2
EMBL X07903
M19437
M24352
AJ271153
PDB 1DM0
1R4Q
PDBsum 1DM0
1R4Q
ProteinModelPortal Q9FBI2
SMR Q9FBI2
PRIDE Q9FBI2
EvolutionaryTrace Q9FBI2
GO GO:0030598
GO:0017148
Gene3D 3.40.420.10
4.10.470.10
InterPro IPR001574
IPR017988
IPR016138
IPR016139
IPR016331
Pfam PF00161
PIRSF PIRSF001924
SUPFAM SSF56371
PROSITE PS00275

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0017148

negative regulation of translation

PMID:19139230[1]

ECO:0000314

P

Figure 3 shows a drastic decrease in protein synthesis in presence of StxA

complete

involved_in

GO:0009405

pathogenesis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0090729

P

Seeded From UniProt

complete

involved_in

GO:0017148

negative regulation of translation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001574
InterPro:IPR016138
InterPro:IPR016331
InterPro:IPR017988
InterPro:IPR036041

P

Seeded From UniProt

complete

enables

GO:0030598

rRNA N-glycosylase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001574
InterPro:IPR016138
InterPro:IPR016331
InterPro:IPR017988
InterPro:IPR036041

F

Seeded From UniProt

complete

enables

GO:0030598

rRNA N-glycosylase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.2.2.22

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

involved_in

GO:0017148

negative regulation of translation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0652

P

Seeded From UniProt

complete

enables

GO:0090729

toxin activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0800

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Quiñones, B et al. (2009) Novel cell-based method to detect Shiga toxin 2 from Escherichia coli O157:H7 and inhibitors of toxin activity. Appl. Environ. Microbiol. 75 1410-6 PubMed GONUTS page