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SGD:CKS1

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Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) CKS1 ( synonyms: YBR135W )
Protein Name(s) Cyclin-dependent protein kinase regulatory subunit and adaptor,
External Links
SGD S000000339

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000307

cyclin-dependent protein kinase holoenzyme complex

SGD_REF:S000039561
PMID:2664468[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000074185
PMID:14562095[2]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000074185
PMID:14562095[2]

IDA: Inferred from Direct Assay

C

From SGD

GO:0006338

chromatin remodeling

SGD_REF:S000136817
PMID:20855529[3]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006351

transcription, DNA-dependent

SGD_REF:S000080329
PMID:15629725[4]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0007049

cell cycle

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000789

P

From SGD

GO:0007049

cell cycle

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0131

P

From SGD

GO:0016538

cyclin-dependent protein kinase regulator activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000789

F

From SGD

GO:0030295

protein kinase activator activity

SGD_REF:S000062128
PMID:10913169[5]

IDA: Inferred from Direct Assay

F

From SGD

GO:0042393

histone binding

SGD_REF:S000136817
PMID:20855529[3]

IDA: Inferred from Direct Assay

F

From SGD

GO:0043130

ubiquitin binding

SGD_REF:S000120201
PMID:17198374[6]

IDA: Inferred from Direct Assay

F

From SGD

GO:0045893

positive regulation of transcription, DNA-dependent

SGD_REF:S000134262
PMID:20516216[7]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0051301

cell division

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0132

P

From SGD

GO:0051726

regulation of cell cycle

SGD_REF:S000058495

TAS: Traceable Author Statement

P

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Hadwiger, JA et al. (1989) The Saccharomyces cerevisiae CKS1 gene, a homolog of the Schizosaccharomyces pombe suc1+ gene, encodes a subunit of the Cdc28 protein kinase complex. Mol. Cell. Biol. 9 2034-41 PubMed GONUTS page
  2. 2.0 2.1 Huh, WK et al. (2003) Global analysis of protein localization in budding yeast. Nature 425 686-91 PubMed GONUTS page
  3. 3.0 3.1 Chaves, S et al. (2010) Cks1, Cdk1, and the 19S proteasome collaborate to regulate gene induction-dependent nucleosome eviction in yeast. Mol. Cell. Biol. 30 5284-94 PubMed GONUTS page
  4. Yu, VP et al. (2005) A kinase-independent function of Cks1 and Cdk1 in regulation of transcription. Mol. Cell 17 145-51 PubMed GONUTS page
  5. Reynard, GJ et al. (2000) Cks1 is required for G(1) cyclin-cyclin-dependent kinase activity in budding yeast. Mol. Cell. Biol. 20 5858-64 PubMed GONUTS page
  6. Tempé, D et al. (2007) The alpha helix of ubiquitin interacts with yeast cyclin-dependent kinase subunit CKS1. Biochemistry 46 45-54 PubMed GONUTS page
  7. Holic, R et al. (2010) Cks1 activates transcription by binding to the ubiquitylated proteasome. Mol. Cell. Biol. 30 3894-901 PubMed GONUTS page
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