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SGD:CHK1

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Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) CHK1 ( synonyms: YBR274W )
Protein Name(s) Serine/threonine kinase and DNA damage checkpoint effector,
External Links
SGD S000000478

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000077

DNA damage checkpoint

SGD_REF:S000039903
PMID:10660074[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0000166

nucleotide binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From SGD

GO:0004672

protein kinase activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR002290
InterPro:IPR000719

F

From SGD

GO:0004674

protein serine/threonine kinase activity

SGD_REF:S000039903
PMID:10660074[1]

ISS: Inferred from Sequence or Structural Similarity

protein_id:P34208

F

From SGD

GO:0004674

protein serine/threonine kinase activity

SGD_REF:S000060449
PMID:11390356[2]

IDA: Inferred from Direct Assay

F

From SGD

GO:0004674

protein serine/threonine kinase activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR008271

F

From SGD

GO:0004674

protein serine/threonine kinase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0723

F

From SGD

GO:0005524

ATP binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR017441
InterPro:IPR002290

F

From SGD

GO:0005524

ATP binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

From SGD

GO:0005634

nucleus

SGD_REF:S000060449
PMID:11390356[2]

IPI: Inferred from Physical Interaction

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

From SGD

GO:0006468

protein phosphorylation

SGD_REF:S000039903
PMID:10660074[1]

ISS: Inferred from Sequence or Structural Similarity

protein_id:P34208

P

From SGD

GO:0006468

protein phosphorylation

SGD_REF:S000060449
PMID:11390356[2]

IDA: Inferred from Direct Assay

P

From SGD

GO:0006468

protein phosphorylation

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR008271
InterPro:IPR002290

P

From SGD

GO:0006974

response to DNA damage stimulus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0227

P

From SGD

GO:0007049

cell cycle

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0131

P

From SGD

GO:0016301

kinase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

F

From SGD

GO:0016310

phosphorylation

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

P

From SGD

GO:0016740

transferase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

From SGD

GO:0016772

transferase activity, transferring phosphorus-containing groups

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR011009

F

From SGD

GO:0048478

replication fork protection

SGD_REF:S000126887
PMID:18593882[3]

IGI: Inferred from Genetic Interaction

SGD:S000005559
SGD:S000006074

P

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Liu, Y et al. (2000) Characterization of a Saccharomyces cerevisiae homologue of Schizosaccharomyces pombe Chk1 involved in DNA-damage-induced M-phase arrest. Mol. Gen. Genet. 262 1132-46 PubMed GONUTS page
  2. 2.0 2.1 2.2 Wang, H et al. (2001) Pds1 phosphorylation in response to DNA damage is essential for its DNA damage checkpoint function. Genes Dev. 15 1361-72 PubMed GONUTS page
  3. Segurado, M & Diffley, JF (2008) Separate roles for the DNA damage checkpoint protein kinases in stabilizing DNA replication forks. Genes Dev. 22 1816-27 PubMed GONUTS page
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