It is now the 1st OPEN Period for CACAO Fall 2017! It will end on Sunday September 24, 2017 at 11:59 pm CDT
This is your chance to make annotations OR challenge other team's annotations. You may also DEFEND or suggest improvements to your own annotations IF they have been challenged. Please note, although we ENCOURAGE challenges, an excess of identical challenges that do not appear to be applicable to the annotation or well thought out will be considered spam and ignored.

Have any questions? Please email us at ecoliwiki@gmail.com

SGD:CHD1

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) CHD1 ( synonyms: YER164W )
Protein Name(s) Chromatin remodeler that regulates various aspects of transcription,
External Links
SGD S000000966

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000124

SAGA complex

SGD_REF:S000080442
PMID:15647753[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0000166

nucleotide binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From SGD

GO:0000182

rDNA binding

SGD_REF:S000120691
PMID:17259992[2]

IDA: Inferred from Direct Assay

F

From SGD

GO:0000790

nuclear chromatin

SGD_REF:S000072835
PMID:12504018[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0000790

nuclear chromatin

SGD_REF:S000073040
PMID:12682017[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0001178

regulation of transcriptional start site selection at RNA polymerase II promoter

SGD_REF:S000132405
PMID:19948887[5]

IGI: Inferred from Genetic Interaction

SGD:S000000449

P

From SGD

GO:0003676

nucleic acid binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001650

F

From SGD

GO:0003677

DNA binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000330
InterPro:IPR009057

F

From SGD

GO:0003677

DNA binding

SGD_REF:S000145576
PMID:21623345[6]

IDA: Inferred from Direct Assay

F

From SGD

GO:0003677

DNA binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

From SGD

GO:0004386

helicase activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001650

F

From SGD

GO:0004386

helicase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0347

F

From SGD

GO:0005524

ATP binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001650
InterPro:IPR000330

F

From SGD

GO:0005524

ATP binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

From SGD

GO:0005634

nucleus

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000953

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

From SGD

GO:0005739

mitochondrion

SGD_REF:S000075100
PMID:14576278[7]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005739

mitochondrion

SGD_REF:S000117178
PMID:16823961[8]

IDA: Inferred from Direct Assay

C

From SGD

GO:0006351

transcription, DNA-dependent

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From SGD

GO:0006355

regulation of transcription, DNA-dependent

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From SGD

GO:0006363

termination of RNA polymerase I transcription

SGD_REF:S000120691
PMID:17259992[2]

IGI: Inferred from Genetic Interaction

SGD:S000005831
SGD:S000000449

P

From SGD

GO:0006368

transcription elongation from RNA polymerase II promoter

SGD_REF:S000073040
PMID:12682017[4]

IGI: Inferred from Genetic Interaction

SGD:S000004470

P

From SGD

GO:0006368

transcription elongation from RNA polymerase II promoter

SGD_REF:S000073040
PMID:12682017[4]

IPI: Inferred from Physical Interaction

SGD:S000003213
SGD:S000004470
SGD:S000004534

P

From SGD

GO:0006369

termination of RNA polymerase II transcription

SGD_REF:S000072835
PMID:12504018[3]

IGI: Inferred from Genetic Interaction

SGD:S000000449
SGD:S000005831

P

From SGD

GO:0006369

termination of RNA polymerase II transcription

SGD_REF:S000072835
PMID:12504018[3]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0008094

DNA-dependent ATPase activity

SGD_REF:S000039644
PMID:10811623[9]

IDA: Inferred from Direct Assay

F

From SGD

GO:0016568

chromatin modification

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0156

P

From SGD

GO:0016584

nucleosome positioning

SGD_REF:S000114409
PMID:16468993[10]

IGI: Inferred from Genetic Interaction

SGD:S000000449
SGD:S000005831

P

From SGD

GO:0016584

nucleosome positioning

SGD_REF:S000126647
PMID:17949749[11]

IDA: Inferred from Direct Assay

P

From SGD

GO:0016787

hydrolase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From SGD

GO:0030874

nucleolar chromatin

SGD_REF:S000120691
PMID:17259992[2]

IDA: Inferred from Direct Assay

C

From SGD

GO:0031490

chromatin DNA binding

SGD_REF:S000073040
PMID:12682017[4]

IDA: Inferred from Direct Assay

F

From SGD

GO:0034401

regulation of transcription by chromatin organization

SGD_REF:S000039644
PMID:10811623[9]

IGI: Inferred from Genetic Interaction

SGD:S000005816

P

From SGD

GO:0034401

regulation of transcription by chromatin organization

SGD_REF:S000114409
PMID:16468993[10]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0035064

methylated histone residue binding

SGD_REF:S000080442
PMID:15647753[1]

IDA: Inferred from Direct Assay

F

From SGD

GO:0042766

nucleosome mobilization

SGD_REF:S000114944
PMID:16606615[12]

IDA: Inferred from Direct Assay

P

From SGD

GO:0043044

ATP-dependent chromatin remodeling

SGD_REF:S000039644
PMID:10811623[9]

IDA: Inferred from Direct Assay

P

From SGD

GO:0046695

SLIK (SAGA-like) complex

SGD_REF:S000080442
PMID:15647753[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0071441

negative regulation of histone H3-K14 acetylation

SGD_REF:S000132405
PMID:19948887[5]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:2000104

negative regulation of DNA-dependent DNA replication

SGD_REF:S000125445
PMID:18245327[13]

IGI: Inferred from Genetic Interaction

SGD:S000004534
SGD:S000003175
SGD:S000003704
SGD:S000000264
SGD:S000006074
SGD:S000000340

P

From SGD

GO:2000616

negative regulation of histone H3-K9 acetylation

SGD_REF:S000132405
PMID:19948887[5]

IMP: Inferred from Mutant Phenotype

P

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Pray-Grant, MG et al. (2005) Chd1 chromodomain links histone H3 methylation with SAGA- and SLIK-dependent acetylation. Nature 433 434-8 PubMed GONUTS page
  2. 2.0 2.1 2.2 Jones, HS et al. (2007) RNA polymerase I in yeast transcribes dynamic nucleosomal rDNA. Nat. Struct. Mol. Biol. 14 123-30 PubMed GONUTS page
  3. 3.0 3.1 3.2 Alén, C et al. (2002) A role for chromatin remodeling in transcriptional termination by RNA polymerase II. Mol. Cell 10 1441-52 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Simic, R et al. (2003) Chromatin remodeling protein Chd1 interacts with transcription elongation factors and localizes to transcribed genes. EMBO J. 22 1846-56 PubMed GONUTS page
  5. 5.0 5.1 5.2 Quan, TK & Hartzog, GA (2010) Histone H3K4 and K36 methylation, Chd1 and Rpd3S oppose the functions of Saccharomyces cerevisiae Spt4-Spt5 in transcription. Genetics 184 321-34 PubMed GONUTS page
  6. Ryan, DP et al. (2011) The DNA-binding domain of the Chd1 chromatin-remodelling enzyme contains SANT and SLIDE domains. EMBO J. 30 2596-609 PubMed GONUTS page
  7. Sickmann, A et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc. Natl. Acad. Sci. U.S.A. 100 13207-12 PubMed GONUTS page
  8. Reinders, J et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J. Proteome Res. 5 1543-54 PubMed GONUTS page
  9. 9.0 9.1 9.2 Tran, HG et al. (2000) The chromo domain protein chd1p from budding yeast is an ATP-dependent chromatin-modifying factor. EMBO J. 19 2323-31 PubMed GONUTS page
  10. 10.0 10.1 Xella, B et al. (2006) The ISWI and CHD1 chromatin remodelling activities influence ADH2 expression and chromatin organization. Mol. Microbiol. 59 1531-41 PubMed GONUTS page
  11. Ferreira, H et al. (2007) Histone modifications influence the action of Snf2 family remodelling enzymes by different mechanisms. J. Mol. Biol. 374 563-79 PubMed GONUTS page
  12. Stockdale, C et al. (2006) Analysis of nucleosome repositioning by yeast ISWI and Chd1 chromatin remodeling complexes. J. Biol. Chem. 281 16279-88 PubMed GONUTS page
  13. Biswas, D et al. (2008) A role for Chd1 and Set2 in negatively regulating DNA replication in Saccharomyces cerevisiae. Genetics 178 649-59 PubMed GONUTS page
<protect>