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SGD:CDC50

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Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) CDC50 ( synonyms: YCR094W )
Protein Name(s) Endosomal protein that interacts with phospholipid flippase Drs2p,
External Links
SGD S000000690

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005768

endosome

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0967

C

From SGD

GO:0005802

trans-Golgi network

SGD_REF:S000076777
PMID:15090616[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0006886

intracellular protein transport

SGD_REF:S000118791
PMID:16956384[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006897

endocytosis

SGD_REF:S000086880
PMID:16195350[3]

IGI: Inferred from Genetic Interaction

SGD:S000004046

P

From SGD

GO:0016020

membrane

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR005045

C

From SGD

GO:0016020

membrane

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From SGD

GO:0016021

integral to membrane

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From SGD

GO:0031902

late endosome membrane

SGD_REF:S000072635
PMID:12589066[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0031902

late endosome membrane

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0151

C

From SGD

GO:0045332

phospholipid translocation

SGD_REF:S000076777
PMID:15090616[1]

IGI: Inferred from Genetic Interaction

SGD:S000005267

P

From SGD

GO:0051666

actin cortical patch localization

SGD_REF:S000086880
PMID:16195350[3]

IGI: Inferred from Genetic Interaction

SGD:S000004046

P

From SGD

contributes_to

GO:0004012

phospholipid-translocating ATPase activity

SGD_REF:S000076777
PMID:15090616[1]

IPI: Inferred from Physical Interaction

SGD:S000000024

F

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Saito, K et al. (2004) Cdc50p, a protein required for polarized growth, associates with the Drs2p P-type ATPase implicated in phospholipid translocation in Saccharomyces cerevisiae. Mol. Biol. Cell 15 3418-32 PubMed GONUTS page
  2. Chen, S et al. (2006) Roles for the Drs2p-Cdc50p complex in protein transport and phosphatidylserine asymmetry of the yeast plasma membrane. Traffic 7 1503-17 PubMed GONUTS page
  3. 3.0 3.1 Kishimoto, T et al. (2005) Defects in structural integrity of ergosterol and the Cdc50p-Drs2p putative phospholipid translocase cause accumulation of endocytic membranes, onto which actin patches are assembled in yeast. Mol. Biol. Cell 16 5592-609 PubMed GONUTS page
  4. Misu, K et al. (2003) Cdc50p, a conserved endosomal membrane protein, controls polarized growth in Saccharomyces cerevisiae. Mol. Biol. Cell 14 730-47 PubMed GONUTS page
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