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SGD:CDC39

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Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) CDC39 ( synonyms: YCR093W, CCR4-NOT core subunit CDC39, NOT1, ROS1, SMD6 )
Protein Name(s) Component of the CCR4-NOT transcriptional complex,
External Links
SGD S000000689

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000122

negative regulation of transcription from RNA polymerase II promoter

SGD_REF:S000054264
PMID:7926748[1]

TAS: Traceable Author Statement

P

From SGD

GO:0000288

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

SGD_REF:S000069437
PMID:11889048[2]

IDA: Inferred from Direct Assay

P

From SGD

GO:0000288

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

SGD_REF:S000069437
PMID:11889048[2]

IGI: Inferred from Genetic Interaction

P

From SGD

GO:0000288

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

SGD_REF:S000069437
PMID:11889048[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0000289

nuclear-transcribed mRNA poly(A) tail shortening

SGD_REF:S000069437
PMID:11889048[2]

IDA: Inferred from Direct Assay

P

From SGD

GO:0000749

response to pheromone involved in conjugation with cellular fusion

SGD_REF:S000040388
PMID:2099190[3]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0003674

molecular function

SGD_REF:S000069584

ND: No biological Data available

F

From SGD

GO:0005634

nucleus

SGD_REF:S000054264
PMID:7926748[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000069437
PMID:11889048[2]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0086

C

From SGD

GO:0006351

transcription, DNA-dependent

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From SGD

GO:0006355

regulation of transcription, DNA-dependent

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From SGD

GO:0006357

regulation of transcription from RNA polymerase II promoter

SGD_REF:S000042122
PMID:10490603[4]

IPI: Inferred from Physical Interaction

P

From SGD

GO:0006368

transcription elongation from RNA polymerase II promoter

SGD_REF:S000074806
PMID:11404327[5]

IGI: Inferred from Genetic Interaction

SGD:S000004470

P

From SGD

GO:0006368

transcription elongation from RNA polymerase II promoter

SGD_REF:S000074806
PMID:11404327[5]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0007124

pseudohyphal growth

SGD_REF:S000042772
PMID:9055077[6]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0030015

CCR4-NOT core complex

SGD_REF:S000042122
PMID:10490603[4]

IPI: Inferred from Physical Interaction

C

From SGD

GO:0032968

positive regulation of transcription elongation from RNA polymerase II promoter

SGD_REF:S000145305
PMID:21406554[7]

IDA: Inferred from Direct Assay

P

From SGD

GO:0032968

positive regulation of transcription elongation from RNA polymerase II promoter

SGD_REF:S000145305
PMID:21406554[7]

IPI: Inferred from Physical Interaction

SGD:S000002299

P

From SGD

GO:0051726

regulation of cell cycle

SGD_REF:S000041086
PMID:2680756[8]

IMP: Inferred from Mutant Phenotype

P

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Collart, MA & Struhl, K (1994) NOT1(CDC39), NOT2(CDC36), NOT3, and NOT4 encode a global-negative regulator of transcription that differentially affects TATA-element utilization. Genes Dev. 8 525-37 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Tucker, M et al. (2002) Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae. EMBO J. 21 1427-36 PubMed GONUTS page
  3. Neiman, AM et al. (1990) CDC36 and CDC39 are negative elements in the signal transduction pathway of yeast. Cell Regul. 1 391-401 PubMed GONUTS page
  4. 4.0 4.1 Bai, Y et al. (1999) The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5. Mol. Cell. Biol. 19 6642-51 PubMed GONUTS page
  5. 5.0 5.1 Denis, CL et al. (2001) Genetic evidence supports a role for the yeast CCR4-NOT complex in transcriptional elongation. Genetics 158 627-34 PubMed GONUTS page
  6. Mösch, HU & Fink, GR (1997) Dissection of filamentous growth by transposon mutagenesis in Saccharomyces cerevisiae. Genetics 145 671-84 PubMed GONUTS page
  7. 7.0 7.1 Kruk, JA et al. (2011) The multifunctional Ccr4-Not complex directly promotes transcription elongation. Genes Dev. 25 581-93 PubMed GONUTS page
  8. Shuster, EO & Byers, B (1989) Pachytene arrest and other meiotic effects of the start mutations in Saccharomyces cerevisiae. Genetics 123 29-43 PubMed GONUTS page
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