It is now the 5th OPEN Period for CACAO Fall 2017! It will end on Tuesday November 21, 2017 at 11:59 pm CST
This is your chance to make annotations OR challenge other team's annotations. You may also DEFEND or suggest improvements to your own annotations IF they have been challenged. Please note, although we ENCOURAGE challenges, an excess of identical challenges that do not appear to be applicable to the annotation or well thought out will be considered spam and ignored.

Have any questions? Please email us at ecoliwiki@gmail.com

SGD:CDC10

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) CDC10 ( synonyms: YCR002C, septin CDC10 )
Protein Name(s) Component of the septin ring, required for cytokinesis,
External Links
SGD S000000595

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000144

cellular bud neck septin ring

SGD_REF:S000044147
PMID:9884239[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0000166

nucleotide binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From SGD

GO:0000921

septin ring assembly

SGD_REF:S000077127
PMID:14993234[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0001400

mating projection base

SGD_REF:S000126719
PMID:18552279[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0003924

GTPase activity

SGD_REF:S000077127
PMID:14993234[2]

IDA: Inferred from Direct Assay

F

From SGD

GO:0005198

structural molecule activity

SGD_REF:S000126669
PMID:18550837[4]

IDA: Inferred from Direct Assay

F

From SGD

GO:0005525

GTP binding

SGD_REF:S000121415
PMID:14597621[5]

IDA: Inferred from Direct Assay

F

From SGD

GO:0005525

GTP binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000038

F

From SGD

GO:0005525

GTP binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0342

F

From SGD

GO:0005545

1-phosphatidylinositol binding

SGD_REF:S000072964
PMID:12665577[6]

IDA: Inferred from Direct Assay

F

From SGD

GO:0005628

prospore membrane

SGD_REF:S000127911
PMID:18826657[7]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005876

spindle microtubule

SGD_REF:S000127911
PMID:18826657[7]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005935

cellular bud neck

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0029

C

From SGD

GO:0007049

cell cycle

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000038

P

From SGD

GO:0007049

cell cycle

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0131

P

From SGD

GO:0010458

exit from mitosis

SGD_REF:S000072991
PMID:12699621[8]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0016020

membrane

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From SGD

GO:0016020

membrane

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0162

C

From SGD

GO:0030011

maintenance of cell polarity

SGD_REF:S000044053
PMID:10882120[9]

IC: Inferred by Curator

GO:0031105

P

From SGD

GO:0031105

septin complex

SGD_REF:S000052983
PMID:9813094[10]

IPI: Inferred from Physical Interaction

SGD:S000004306

C

From SGD

GO:0031105

septin complex

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR016491

C

From SGD

GO:0031105

septin complex

SGD_REF:S000126669
PMID:18550837[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0032160

septin filament array

SGD_REF:S000077562
PMID:15282341[11]

IDA: Inferred from Direct Assay

C

From SGD

GO:0032947

protein complex scaffold

SGD_REF:S000081753
PMID:15901837[12]

IDA: Inferred from Direct Assay

F

From SGD

GO:0033205

cell cycle cytokinesis

SGD_REF:S000073001
PMID:12636916[13]

IDA: Inferred from Direct Assay

P

From SGD

GO:0042764

ascospore-type prospore

SGD_REF:S000127406
PMID:18701287[14]

IDA: Inferred from Direct Assay

C

From SGD

GO:0043332

mating projection tip

SGD_REF:S000128539
PMID:19053807[15]

IDA: Inferred from Direct Assay

C

From SGD

GO:0043934

sporulation

SGD_REF:S000127406
PMID:18701287[14]

IDA: Inferred from Direct Assay

P

From SGD

GO:0051301

cell division

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0132

P

From SGD

GO:0072687

meiotic spindle

SGD_REF:S000127911
PMID:18826657[7]

IDA: Inferred from Direct Assay

C

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Cid, VJ et al. (1998) Cell integrity and morphogenesis in a budding yeast septin mutant. Microbiology (Reading, Engl.) 144 ( Pt 12) 3463-74 PubMed GONUTS page
  2. 2.0 2.1 Versele, M & Thorner, J (2004) Septin collar formation in budding yeast requires GTP binding and direct phosphorylation by the PAK, Cla4. J. Cell Biol. 164 701-15 PubMed GONUTS page
  3. Bharucha, JP et al. (2008) Saccharomyces cerevisiae Afr1 protein is a protein phosphatase 1/Glc7-targeting subunit that regulates the septin cytoskeleton during mating. Eukaryotic Cell 7 1246-55 PubMed GONUTS page
  4. 4.0 4.1 Bertin, A et al. (2008) Saccharomyces cerevisiae septins: supramolecular organization of heterooligomers and the mechanism of filament assembly. Proc. Natl. Acad. Sci. U.S.A. 105 8274-9 PubMed GONUTS page
  5. Vrabioiu, AM et al. (2004) The majority of the Saccharomyces cerevisiae septin complexes do not exchange guanine nucleotides. J. Biol. Chem. 279 3111-8 PubMed GONUTS page
  6. Casamayor, A & Snyder, M (2003) Molecular dissection of a yeast septin: distinct domains are required for septin interaction, localization, and function. Mol. Cell. Biol. 23 2762-77 PubMed GONUTS page
  7. 7.0 7.1 7.2 Pablo-Hernando, ME et al. (2008) Septins localize to microtubules during nutritional limitation in Saccharomyces cerevisiae. BMC Cell Biol. 9 55 PubMed GONUTS page
  8. Castillon, GA et al. (2003) Septins have a dual role in controlling mitotic exit in budding yeast. Curr. Biol. 13 654-8 PubMed GONUTS page
  9. Barral, Y et al. (2000) Compartmentalization of the cell cortex by septins is required for maintenance of cell polarity in yeast. Mol. Cell 5 841-51 PubMed GONUTS page
  10. Frazier, JA et al. (1998) Polymerization of purified yeast septins: evidence that organized filament arrays may not be required for septin function. J. Cell Biol. 143 737-49 PubMed GONUTS page
  11. Versele, M et al. (2004) Protein-protein interactions governing septin heteropentamer assembly and septin filament organization in Saccharomyces cerevisiae. Mol. Biol. Cell 15 4568-83 PubMed GONUTS page
  12. Kozubowski, L et al. (2005) Role of the septin ring in the asymmetric localization of proteins at the mother-bud neck in Saccharomyces cerevisiae. Mol. Biol. Cell 16 3455-66 PubMed GONUTS page
  13. Dobbelaere, J et al. (2003) Phosphorylation-dependent regulation of septin dynamics during the cell cycle. Dev. Cell 4 345-57 PubMed GONUTS page
  14. 14.0 14.1 McMurray, MA & Thorner, J (2008) Septin stability and recycling during dynamic structural transitions in cell division and development. Curr. Biol. 18 1203-8 PubMed GONUTS page
  15. Narayanaswamy, R et al. (2009) Systematic definition of protein constituents along the major polarization axis reveals an adaptive reuse of the polarization machinery in pheromone-treated budding yeast. J. Proteome Res. 8 6-19 PubMed GONUTS page
<protect>