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SGD:CCA1

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Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) CCA1 ( synonyms: YER168C, TNT1 )
Protein Name(s) ATP (CTP):tRNA-specific tRNA nucleotidyltransferase,
External Links
SGD S000000970

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0009022

tRNA nucleotidyltransferase activity

PMID:18302315[1]

ISA: Inferred from Sequence Alignment

F

Figure 1. ClustalW alignment of tRNA nucleotidyltransferase sequences optimized manually: comparing a mutant of the gene with no tRNA nucleotidyltransferase activity was sequenced against the wild type with only a single Glu to Lys substitution at position 189 of the protein implicating this change alone in generating the ts phenotype.

Missing: with/from

GO:0000166

nucleotide binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From SGD

GO:0001680

tRNA 3'-terminal CCA addition

SGD_REF:S000056592
PMID:1634528[2]

IDA: Inferred from Direct Assay

P

From SGD

GO:0001680

tRNA 3'-terminal CCA addition

SGD_REF:S000124037

IEA: Inferred from Electronic Annotation

EC:2.7.7.72

P

From SGD

GO:0003723

RNA binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR002646

F

From SGD

GO:0003723

RNA binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0694

F

From SGD

GO:0004810

tRNA adenylyltransferase activity

SGD_REF:S000056592
PMID:1634528[2]

IDA: Inferred from Direct Assay

F

From SGD

GO:0005524

ATP binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

From SGD

GO:0005634

nucleus

SGD_REF:S000044248
PMID:8617732[3]

NAS: Non-traceable Author Statement

C

From SGD

GO:0005634

nucleus

SGD_REF:S000050706
PMID:8175766[4]

NAS: Non-traceable Author Statement

C

From SGD

GO:0005634

nucleus

SGD_REF:S000056592
PMID:1634528[2]

NAS: Non-traceable Author Statement

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000044248
PMID:8617732[3]

NAS: Non-traceable Author Statement

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000050706
PMID:8175766[4]

NAS: Non-traceable Author Statement

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000056592
PMID:1634528[2]

NAS: Non-traceable Author Statement

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0086

C

From SGD

GO:0005739

mitochondrion

SGD_REF:S000117178
PMID:16823961[5]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005739

mitochondrion

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0496

C

From SGD

GO:0005739

mitochondrion

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0173

C

From SGD

GO:0005759

mitochondrial matrix

SGD_REF:S000056592
PMID:1634528[2]

IDA: Inferred from Direct Assay

C

From SGD

GO:0006396

RNA processing

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR002646

P

From SGD

GO:0016740

transferase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

From SGD

GO:0016779

nucleotidyltransferase activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR002646

F

From SGD

GO:0016779

nucleotidyltransferase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0548

F

From SGD

GO:0052927

CTP:tRNA cytidylyltransferase activity

SGD_REF:S000124037

IEA: Inferred from Electronic Annotation

EC:2.7.7.72

F

From SGD

GO:0052928

CTP:3'-cytidine-tRNA cytidylyltransferase activity

SGD_REF:S000124037

IEA: Inferred from Electronic Annotation

EC:2.7.7.72

F

From SGD

GO:0052929

ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity

SGD_REF:S000124037

IEA: Inferred from Electronic Annotation

EC:2.7.7.72

F

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Shan, X et al. (2008) Characterization of a temperature-sensitive mutation that impairs the function of yeast tRNA nucleotidyltransferase. Yeast 25 219-33 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Chen, JY et al. (1992) Cytoplasmic and mitochondrial tRNA nucleotidyltransferase activities are derived from the same gene in the yeast Saccharomyces cerevisiae. J. Biol. Chem. 267 14879-83 PubMed GONUTS page
  3. 3.0 3.1 Wolfe, CL et al. (1996) Mechanisms leading to and the consequences of altering the normal distribution of ATP(CTP):tRNA nucleotidyltransferase in yeast. J. Biol. Chem. 271 4679-86 PubMed GONUTS page
  4. 4.0 4.1 Wolfe, CL et al. (1994) Interplay of heterogeneous transcriptional start sites and translational selection of AUGs dictate the production of mitochondrial and cytosolic/nuclear tRNA nucleotidyltransferase from the same gene in yeast. J. Biol. Chem. 269 13361-6 PubMed GONUTS page
  5. Reinders, J et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J. Proteome Res. 5 1543-54 PubMed GONUTS page
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