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SGD:BRR2

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Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) BRR2 ( synonyms: YER172C, PRP44, RSS1, SLT22, SNU246 )
Protein Name(s) RNA-dependent ATPase RNA helicase (DEIH box),
External Links
SGD S000000974

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From SGD

GO:0000388

spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)

SGD_REF:S000061922
PMID:9705931[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0003676

nucleic acid binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR011545
InterPro:IPR001650

F

From SGD

GO:0004004

ATP-dependent RNA helicase activity

SGD_REF:S000056328
PMID:8649518[2]

IDA: Inferred from Direct Assay

F

From SGD

GO:0004004

ATP-dependent RNA helicase activity

SGD_REF:S000056328
PMID:8649518[2]

IMP: Inferred from Mutant Phenotype

F

From SGD

GO:0004004

ATP-dependent RNA helicase activity

SGD_REF:S000061922
PMID:9705931[1]

IMP: Inferred from Mutant Phenotype

F

From SGD

GO:0004386

helicase activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001650

F

From SGD

GO:0004386

helicase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0347

F

From SGD

GO:0005524

ATP binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR011545
InterPro:IPR001650

F

From SGD

GO:0005524

ATP binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

From SGD

GO:0005634

nucleus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

From SGD

GO:0005681

spliceosomal complex

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0747

C

From SGD

GO:0005682

U5 snRNP

SGD_REF:S000066234
PMID:11720284[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0006397

mRNA processing

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0507

P

From SGD

GO:0008026

ATP-dependent helicase activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR011545

F

From SGD

GO:0008380

RNA splicing

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0508

P

From SGD

GO:0016787

hydrolase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From SGD

GO:0046540

U4/U6 x U5 tri-snRNP complex

SGD_REF:S000039461
PMID:10449419[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0046540

U4/U6 x U5 tri-snRNP complex

SGD_REF:S000053606
PMID:8670905[5]

IDA: Inferred from Direct Assay

C

From SGD

GO:0046540

U4/U6 x U5 tri-snRNP complex

SGD_REF:S000056376
PMID:10377396[6]

IDA: Inferred from Direct Assay

C

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Raghunathan, PL & Guthrie, C (1998) RNA unwinding in U4/U6 snRNPs requires ATP hydrolysis and the DEIH-box splicing factor Brr2. Curr. Biol. 8 847-55 PubMed GONUTS page
  2. 2.0 2.1 Xu, D et al. (1996) An RNA-dependent ATPase associated with U2/U6 snRNAs in pre-mRNA splicing. Nature 381 709-13 PubMed GONUTS page
  3. Stevens, SW et al. (2001) Biochemical and genetic analyses of the U5, U6, and U4/U6 x U5 small nuclear ribonucleoproteins from Saccharomyces cerevisiae. RNA 7 1543-53 PubMed GONUTS page
  4. Gottschalk, A et al. (1999) Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6.U5] tri-snRNP. EMBO J. 18 4535-48 PubMed GONUTS page
  5. Lauber, J et al. (1996) The HeLa 200 kDa U5 snRNP-specific protein and its homologue in Saccharomyces cerevisiae are members of the DEXH-box protein family of putative RNA helicases. EMBO J. 15 4001-15 PubMed GONUTS page
  6. Stevens, SW & Abelson, J (1999) Purification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins. Proc. Natl. Acad. Sci. U.S.A. 96 7226-31 PubMed GONUTS page
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