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SGD:BEM2

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Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) BEM2 ( synonyms: YER155C, IPL2, SUP9, TSL1 )
Protein Name(s) Rho GTPase activating protein (RhoGAP),
External Links
SGD S000000957

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000131

incipient cellular bud site

SGD_REF:S000124293
PMID:17914457[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005085

guanyl-nucleotide exchange factor activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001895
InterPro:IPR000651

F

From SGD

GO:0005096

GTPase activator activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0343

F

From SGD

GO:0005100

Rho GTPase activator activity

SGD_REF:S000039493
PMID:7962098[2]

IDA: Inferred from Direct Assay

F

From SGD

GO:0005543

phospholipid binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001849

F

From SGD

GO:0005622

intracellular

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000651
InterPro:IPR001895
InterPro:IPR000198
InterPro:IPR008936

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000124293
PMID:17914457[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005739

mitochondrion

SGD_REF:S000075100
PMID:14576278[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005739

mitochondrion

SGD_REF:S000117178
PMID:16823961[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005886

plasma membrane

SGD_REF:S000124293
PMID:17914457[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005934

cellular bud tip

SGD_REF:S000124293
PMID:17914457[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005938

cell cortex

SGD_REF:S000124293
PMID:17914457[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0007165

signal transduction

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR008936
InterPro:IPR000198

P

From SGD

GO:0007264

small GTPase mediated signal transduction

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR001895

P

From SGD

GO:0030010

establishment of cell polarity

SGD_REF:S000058399
PMID:9891811[5]

TAS: Traceable Author Statement

P

From SGD

GO:0030036

actin cytoskeleton organization

SGD_REF:S000053805
PMID:7579704[6]

IGI: Inferred from Genetic Interaction

P

From SGD

GO:0030036

actin cytoskeleton organization

SGD_REF:S000058399
PMID:9891811[5]

TAS: Traceable Author Statement

P

From SGD

GO:0031505

fungal-type cell wall organization

SGD_REF:S000058399
PMID:9891811[5]

TAS: Traceable Author Statement

P

From SGD

GO:0035024

negative regulation of Rho protein signal transduction

SGD_REF:S000124293
PMID:17914457[1]

IGI: Inferred from Genetic Interaction

SGD:S000006036

P

From SGD

GO:0035024

negative regulation of Rho protein signal transduction

SGD_REF:S000124293
PMID:17914457[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0043332

mating projection tip

SGD_REF:S000124293
PMID:17914457[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0043547

positive regulation of GTPase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0343

P

From SGD

GO:0051056

regulation of small GTPase mediated signal transduction

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000651

P

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Knaus, M et al. (2007) Phosphorylation of Bem2p and Bem3p may contribute to local activation of Cdc42p at bud emergence. EMBO J. 26 4501-13 PubMed GONUTS page
  2. Peterson, J et al. (1994) Interactions between the bud emergence proteins Bem1p and Bem2p and Rho-type GTPases in yeast. J. Cell Biol. 127 1395-406 PubMed GONUTS page
  3. Sickmann, A et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc. Natl. Acad. Sci. U.S.A. 100 13207-12 PubMed GONUTS page
  4. Reinders, J et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J. Proteome Res. 5 1543-54 PubMed GONUTS page
  5. 5.0 5.1 5.2 Madden, K & Snyder, M (1998) Cell polarity and morphogenesis in budding yeast. Annu. Rev. Microbiol. 52 687-744 PubMed GONUTS page
  6. Wang, T & Bretscher, A (1995) The rho-GAP encoded by BEM2 regulates cytoskeletal structure in budding yeast. Mol. Biol. Cell 6 1011-24 PubMed GONUTS page
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