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SGD:BCY1

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Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) BCY1 ( synonyms: YIL033C, SRA1 )
Protein Name(s) Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA),
External Links
SGD S000001295

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From SGD

GO:0001932

regulation of protein phosphorylation

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR002373
InterPro:IPR012198

P

From SGD

GO:0004862

cAMP-dependent protein kinase inhibitor activity

SGD_REF:S000043708
PMID:3037314[1]

IDA: Inferred from Direct Assay

F

From SGD

GO:0004862

cAMP-dependent protein kinase inhibitor activity

SGD_REF:S000055679
PMID:6292221[2]

IMP: Inferred from Mutant Phenotype

F

From SGD

GO:0005634

nucleus

SGD_REF:S000056327
PMID:3288487[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000059459
PMID:11134339[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000069459
PMID:11914276[5]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000126103
PMID:18417610[6]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000059459
PMID:11134339[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000069459
PMID:11914276[5]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0086

C

From SGD

GO:0005886

plasma membrane

SGD_REF:S000061855
PMID:2831892[7]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005952

cAMP-dependent protein kinase complex

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR002373
InterPro:IPR012198

C

From SGD

GO:0007165

signal transduction

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR003117

P

From SGD

GO:0008603

cAMP-dependent protein kinase regulator activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR012198
InterPro:IPR003117
InterPro:IPR002373

F

From SGD

GO:0030552

cAMP binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0116

F

From SGD

GO:0046580

negative regulation of Ras protein signal transduction

SGD_REF:S000043708
PMID:3037314[1]

IDA: Inferred from Direct Assay

P

From SGD

GO:0046580

negative regulation of Ras protein signal transduction

SGD_REF:S000043708
PMID:3037314[1]

IMP: Inferred from Mutant Phenotype

P

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Toda, T et al. (1987) Cloning and characterization of BCY1, a locus encoding a regulatory subunit of the cyclic AMP-dependent protein kinase in Saccharomyces cerevisiae. Mol. Cell. Biol. 7 1371-7 PubMed GONUTS page
  2. Uno, I et al. (1982) Characterization of cyclic AMP-requiring yeast mutants altered in the regulatory subunit of protein kinase. J. Biol. Chem. 257 14110-5 PubMed GONUTS page
  3. Uno, I et al. (1988) Localization of the regulatory subunit of cAMP-dependent protein kinase in Saccharomyces cerevisiae. Exp. Cell Res. 176 360-5 PubMed GONUTS page
  4. 4.0 4.1 Griffioen, G et al. (2001) Nucleocytoplasmic distribution of budding yeast protein kinase A regulatory subunit Bcy1 requires Zds1 and is regulated by Yak1-dependent phosphorylation of its targeting domain. Mol. Cell. Biol. 21 511-23 PubMed GONUTS page
  5. 5.0 5.1 Kumar, A et al. (2002) Subcellular localization of the yeast proteome. Genes Dev. 16 707-19 PubMed GONUTS page
  6. Bharucha, N et al. (2008) Analysis of the yeast kinome reveals a network of regulated protein localization during filamentous growth. Mol. Biol. Cell 19 2708-17 PubMed GONUTS page
  7. Behrens, MM & Mazón, MJ (1988) Yeast cAMP-dependent protein kinase can be associated to the plasma membrane. Biochem. Biophys. Res. Commun. 151 561-7 PubMed GONUTS page
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