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SGD:ATG15

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Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) ATG15 ( synonyms: YCR068W, AUT5, CVT17 )
Protein Name(s) Lipase required for lysis of autophagic bodies and Cvt bodies,
External Links
SGD S000000664

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000139

Golgi membrane

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0134

C

From SGD

GO:0004806

triglyceride lipase activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR002921

F

From SGD

GO:0004806

triglyceride lipase activity

SGD_REF:S000124037

IEA: Inferred from Electronic Annotation

EC:3.1.1.3

F

From SGD

GO:0005768

endosome

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0967

C

From SGD

GO:0005775

vacuolar lumen

SGD_REF:S000066067
PMID:11566994[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005783

endoplasmic reticulum

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0256

C

From SGD

GO:0005789

endoplasmic reticulum membrane

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0097

C

From SGD

GO:0005794

Golgi apparatus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0333

C

From SGD

GO:0006624

vacuolar protein processing

SGD_REF:S000060121
PMID:11085977[2]

IDA: Inferred from Direct Assay

P

From SGD

GO:0006624

vacuolar protein processing

SGD_REF:S000060121
PMID:11085977[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006629

lipid metabolic process

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR002921

P

From SGD

GO:0006914

autophagy

SGD_REF:S000060121
PMID:11085977[2]

IDA: Inferred from Direct Assay

P

From SGD

GO:0006914

autophagy

SGD_REF:S000060121
PMID:11085977[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006914

autophagy

SGD_REF:S000066067
PMID:11566994[1]

IDA: Inferred from Direct Assay

P

From SGD

GO:0006914

autophagy

SGD_REF:S000066067
PMID:11566994[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0006914

autophagy

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0072

P

From SGD

GO:0016020

membrane

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From SGD

GO:0016021

integral to membrane

SGD_REF:S000060121
PMID:11085977[2]

IPI: Inferred from Physical Interaction

C

From SGD

GO:0016021

integral to membrane

SGD_REF:S000060121
PMID:11085977[2]

ISS: Inferred from Sequence or Structural Similarity

C

From SGD

GO:0016021

integral to membrane

SGD_REF:S000072757
PMID:12499386[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0016021

integral to membrane

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From SGD

GO:0016042

lipid catabolic process

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0442

P

From SGD

GO:0016298

lipase activity

SGD_REF:S000060121
PMID:11085977[2]

ISM: Inferred from Sequence Model

Prosite:PS00120

F

From SGD

GO:0016787

hydrolase activity

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From SGD

GO:0030397

membrane disassembly

SGD_REF:S000060121
PMID:11085977[2]

IDA: Inferred from Direct Assay

P

From SGD

GO:0030397

membrane disassembly

SGD_REF:S000060121
PMID:11085977[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0030397

membrane disassembly

SGD_REF:S000072757
PMID:12499386[3]

IDA: Inferred from Direct Assay

P

From SGD

GO:0031902

late endosome membrane

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0224

C

From SGD

GO:0032585

multivesicular body membrane

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0175

C

From SGD

GO:0034496

multivesicular body membrane disassembly

SGD_REF:S000072757
PMID:12499386[3]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0034727

piecemeal microautophagy of nucleus

SGD_REF:S000127377
PMID:18701704[4]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0050253

retinyl-palmitate esterase activity

SGD_REF:S000124037

IEA: Inferred from Electronic Annotation

EC:3.1.1.3

F

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Epple, UD et al. (2001) Aut5/Cvt17p, a putative lipase essential for disintegration of autophagic bodies inside the vacuole. J. Bacteriol. 183 5942-55 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 Teter, SA et al. (2001) Degradation of lipid vesicles in the yeast vacuole requires function of Cvt17, a putative lipase. J. Biol. Chem. 276 2083-7 PubMed GONUTS page
  3. 3.0 3.1 3.2 Epple, UD et al. (2003) Intravacuolar membrane lysis in Saccharomyces cerevisiae. Does vacuolar targeting of Cvt17/Aut5p affect its function? J. Biol. Chem. 278 7810-21 PubMed GONUTS page
  4. Krick, R et al. (2008) Piecemeal microautophagy of the nucleus requires the core macroautophagy genes. Mol. Biol. Cell 19 4492-505 PubMed GONUTS page
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