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SGD:ASK1

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Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) ASK1 ( synonyms: YKL052C )
Protein Name(s) Essential subunit of the Dam1 complex (aka DASH complex),
External Links
SGD S000001535

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000070

mitotic sister chromatid segregation

SGD_REF:S000069052
PMID:11799062[1]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0000775

chromosome, centromeric region

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0137

C

From SGD

GO:0000776

kinetochore

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0995

C

From SGD

GO:0000777

condensed chromosome kinetochore

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0149

C

From SGD

GO:0000778

condensed nuclear chromosome kinetochore

SGD_REF:S000069091
PMID:11756468[2]

IDA: Inferred from Direct Assay

C

From SGD

GO:0000780

condensed nuclear chromosome, centromeric region

SGD_REF:S000069220
PMID:11782438[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005200

structural constituent of cytoskeleton

SGD_REF:S000069091
PMID:11756468[2]

IDA: Inferred from Direct Assay

F

From SGD

GO:0005634

nucleus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

From SGD

GO:0005694

chromosome

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0158

C

From SGD

GO:0005737

cytoplasm

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From SGD

GO:0005819

spindle

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0251

C

From SGD

GO:0005856

cytoskeleton

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0206

C

From SGD

GO:0005874

microtubule

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0493

C

From SGD

GO:0007049

cell cycle

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0131

P

From SGD

GO:0007059

chromosome segregation

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0159

P

From SGD

GO:0007067

mitosis

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0498

P

From SGD

GO:0008608

attachment of spindle microtubules to kinetochore

SGD_REF:S000069091
PMID:11756468[2]

IDA: Inferred from Direct Assay

P

From SGD

GO:0030472

mitotic spindle organization in nucleus

SGD_REF:S000069091
PMID:11756468[2]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:0031110

regulation of microtubule polymerization or depolymerization

SGD_REF:S000080667
PMID:15664196[4]

IDA: Inferred from Direct Assay

P

From SGD

GO:0031110

regulation of microtubule polymerization or depolymerization

SGD_REF:S000080667
PMID:15664196[4]

IPI: Inferred from Physical Interaction

P

From SGD

GO:0042729

DASH complex

SGD_REF:S000069052
PMID:11799062[1]

IDA: Inferred from Direct Assay

C

From SGD

GO:0042729

DASH complex

SGD_REF:S000069052
PMID:11799062[1]

IPI: Inferred from Physical Interaction

C

From SGD

GO:0042729

DASH complex

SGD_REF:S000080444
PMID:15640796[5]

IDA: Inferred from Direct Assay

C

From SGD

GO:0042729

DASH complex

SGD_REF:S000080444
PMID:15640796[5]

IPI: Inferred from Physical Interaction

C

From SGD

GO:0042729

DASH complex

SGD_REF:S000080667
PMID:15664196[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0042729

DASH complex

SGD_REF:S000080667
PMID:15664196[4]

IPI: Inferred from Physical Interaction

C

From SGD

GO:0051301

cell division

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0132

P

From SGD

GO:0051315

attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation

SGD_REF:S000069052
PMID:11799062[1]

IC: Inferred by Curator

GO:0000070

P

From SGD

GO:0051315

attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation

SGD_REF:S000069091
PMID:11756468[2]

IC: Inferred by Curator

GO:0008608

P

From SGD

GO:0072686

mitotic spindle

SGD_REF:S000069091
PMID:11756468[2]

IDA: Inferred from Direct Assay

C

From SGD

contributes_to

GO:0008017

microtubule binding

SGD_REF:S000116677
PMID:16777964[6]

IDA: Inferred from Direct Assay

F

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Li, Y et al. (2002) The mitotic spindle is required for loading of the DASH complex onto the kinetochore. Genes Dev. 16 183-97 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Cheeseman, IM et al. (2001) Implication of a novel multiprotein Dam1p complex in outer kinetochore function. J. Cell Biol. 155 1137-45 PubMed GONUTS page
  3. Janke, C et al. (2002) Four new subunits of the Dam1-Duo1 complex reveal novel functions in sister kinetochore biorientation. EMBO J. 21 181-93 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Westermann, S et al. (2005) Formation of a dynamic kinetochore- microtubule interface through assembly of the Dam1 ring complex. Mol. Cell 17 277-90 PubMed GONUTS page
  5. 5.0 5.1 Miranda, JJ et al. (2005) The yeast DASH complex forms closed rings on microtubules. Nat. Struct. Mol. Biol. 12 138-43 PubMed GONUTS page
  6. Asbury, CL et al. (2006) The Dam1 kinetochore complex harnesses microtubule dynamics to produce force and movement. Proc. Natl. Acad. Sci. U.S.A. 103 9873-8 PubMed GONUTS page
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