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SGD:ASH1

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Species (Taxon ID) Saccharomyces cerevisiae (baker's yeast) (taxon:4932)
Gene Name(s) ASH1 ( synonyms: YKL185W )
Protein Name(s) Zinc-finger inhibitor of HO transcription,
External Links
SGD S000001668

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000987

core promoter proximal region sequence-specific DNA binding

SGD_REF:S000079870
PMID:11171979[1]

IDA: Inferred from Direct Assay

F

From SGD

GO:0001078

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription

SGD_REF:S000079870
PMID:11171979[1]

IMP: Inferred from Mutant Phenotype

F

From SGD

GO:0001078

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription

SGD_REF:S000132051
PMID:19841732[2]

IDA: Inferred from Direct Assay

F

From SGD

GO:0003677

DNA binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

From SGD

GO:0003700

sequence-specific DNA binding transcription factor activity

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000679

F

From SGD

GO:0005634

nucleus

SGD_REF:S000042424
PMID:8625408[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000042425
PMID:8625409[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000045535
PMID:9566907[5]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From SGD

GO:0005634

nucleus

SGD_REF:S000148671

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

From SGD

GO:0005933

cellular bud

SGD_REF:S000042424
PMID:8625408[3]

IDA: Inferred from Direct Assay

C

From SGD

GO:0005933

cellular bud

SGD_REF:S000042425
PMID:8625409[4]

IDA: Inferred from Direct Assay

C

From SGD

GO:0006351

transcription, DNA-dependent

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From SGD

GO:0006355

regulation of transcription, DNA-dependent

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR013088
InterPro:IPR000679

P

From SGD

GO:0006355

regulation of transcription, DNA-dependent

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From SGD

GO:0008270

zinc ion binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR013088
InterPro:IPR000679

F

From SGD

GO:0016568

chromatin modification

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0156

P

From SGD

GO:0033698

Rpd3L complex

SGD_REF:S000113697
PMID:16314178[6]

IDA: Inferred from Direct Assay

C

From SGD

GO:0033698

Rpd3L complex

SGD_REF:S000113735
PMID:16286007[7]

IDA: Inferred from Direct Assay

C

From SGD

GO:0033698

Rpd3L complex

SGD_REF:S000128493
PMID:19040720[8]

IDA: Inferred from Direct Assay

C

From SGD

GO:0043565

sequence-specific DNA binding

SGD_REF:S000124036

IEA: Inferred from Electronic Annotation

InterPro:IPR000679

F

From SGD

GO:0046872

metal ion binding

SGD_REF:S000148669

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From SGD

GO:0070210

Rpd3L-Expanded complex

SGD_REF:S000128493
PMID:19040720[8]

IDA: Inferred from Direct Assay

C

From SGD

GO:1900461

positive regulation of pseudohyphal growth by positive regulation of transcription from RNA polymerase II promoter

SGD_REF:S000059111
PMID:11046133[9]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:1900474

negative regulation of mating type switching by negative regulation of transcription from RNA polymerase II promoter

SGD_REF:S000042424
PMID:8625408[3]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:1900474

negative regulation of mating type switching by negative regulation of transcription from RNA polymerase II promoter

SGD_REF:S000042425
PMID:8625409[4]

IMP: Inferred from Mutant Phenotype

P

From SGD

GO:1900477

negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter

SGD_REF:S000132051
PMID:19841732[2]

IDA: Inferred from Direct Assay

P

From SGD

GO:1900477

negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter

SGD_REF:S000132051
PMID:19841732[2]

IMP: Inferred from Mutant Phenotype

P

From SGD


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Maxon, ME & Herskowitz, I (2001) Ash1p is a site-specific DNA-binding protein that actively represses transcription. Proc. Natl. Acad. Sci. U.S.A. 98 1495-500 PubMed GONUTS page
  2. 2.0 2.1 2.2 Di Talia, S et al. (2009) Daughter-specific transcription factors regulate cell size control in budding yeast. PLoS Biol. 7 e1000221 PubMed GONUTS page
  3. 3.0 3.1 3.2 Bobola, N et al. (1996) Asymmetric accumulation of Ash1p in postanaphase nuclei depends on a myosin and restricts yeast mating-type switching to mother cells. Cell 84 699-709 PubMed GONUTS page
  4. 4.0 4.1 4.2 Sil, A & Herskowitz, I (1996) Identification of asymmetrically localized determinant, Ash1p, required for lineage-specific transcription of the yeast HO gene. Cell 84 711-22 PubMed GONUTS page
  5. Chandarlapaty, S & Errede, B (1998) Ash1, a daughter cell-specific protein, is required for pseudohyphal growth of Saccharomyces cerevisiae. Mol. Cell. Biol. 18 2884-91 PubMed GONUTS page
  6. Carrozza, MJ et al. (2005) Stable incorporation of sequence specific repressors Ash1 and Ume6 into the Rpd3L complex. Biochim. Biophys. Acta 1731 77-87; discussion 75-6 PubMed GONUTS page
  7. Carrozza, MJ et al. (2005) Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription. Cell 123 581-92 PubMed GONUTS page
  8. 8.0 8.1 Shevchenko, A et al. (2008) Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment. Genome Biol. 9 R167 PubMed GONUTS page
  9. Pan, X & Heitman, J (2000) Sok2 regulates yeast pseudohyphal differentiation via a transcription factor cascade that regulates cell-cell adhesion. Mol. Cell. Biol. 20 8364-72 PubMed GONUTS page
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