SCHPO:TSN1

Species (Taxon ID)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). (284812)
Gene Name(s)	tsn1 (synonyms: mug90)
Protein Name(s)	Translin-1 Meiotically up-regulated gene 90 protein Translin homolog
External Links
UniProt	Q9P7V3
EMBL	CU329670
PIR	T50209
RefSeq	NP_594557.2
SMR	Q9P7V3
BioGrid	278209
STRING	4896.SPAC30.03c.1
MaxQB	Q9P7V3
PaxDb	Q9P7V3
PRIDE	Q9P7V3
EnsemblFungi	SPAC30.03c.1
GeneID	2541714
KEGG	spo:SPAC30.03c
EuPathDB	FungiDB:SPAC30.03c
PomBase	SPAC30.03c
HOGENOM	HOG000198374
InParanoid	Q9P7V3
OMA	ARELFCT
PhylomeDB	Q9P7V3
Reactome	R-SPO-426486
PRO	PR:Q9P7V3
Proteomes	UP000002485
GO	GO:0005737 GO:0005829 GO:0005634 GO:0004521 GO:1990605 GO:0035939 GO:0003723 GO:0043565 GO:0003697 GO:0043047 GO:0051321 GO:0008033
CDD	cd14819
Gene3D	1.20.58.190 1.20.58.200
InterPro	IPR033956 IPR016069 IPR002848 IPR016068 IPR036081
PANTHER	PTHR10741 PTHR10741:SF2
Pfam	PF01997
SUPFAM	SSF74784

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0000724	double-strand break repair via homologous recombination	PMID:18062930^[1]	ECO:0000304			P			complete
	GO:0003723	RNA binding	PMID:16043634^[2]	ECO:0000314			F			complete
	GO:0005515	protein binding	PMID:16043634^[2]	ECO:0000021			F			complete
	GO:0005634	nucleus	PMID:16823372^[3]	ECO:0000314			C			complete
	GO:0005634	nucleus	PMID:17072883^[4]	ECO:0000303			C			complete
	GO:0005829	cytosol	PMID:16823372^[3]	ECO:0000314			C			complete
	GO:0006259	DNA metabolic process	PMID:18062930^[1]	ECO:0000303			P			complete
	GO:0006303	double-strand break repair via nonhomologous end joining	PMID:18062930^[1]	ECO:0000304			P			complete
	GO:0043047	single-stranded telomeric DNA binding	PMID:16043634^[2]	ECO:0000314			F			complete
enables	GO:1990605	GU repeat RNA binding	PMID:20081200^[5]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0043047	single-stranded telomeric DNA binding	PMID:16043634^[2]	ECO:0000314	direct assay evidence used in manual assertion		F	occurs_at:(SO:0001863)	Seeded From UniProt	complete
enables	GO:0043047	single-stranded telomeric DNA binding	PMID:16043634^[2]	ECO:0000314	direct assay evidence used in manual assertion		F	occurs_at:(SO:0001862)	Seeded From UniProt	complete
enables	GO:0035939	microsatellite binding	PMID:20081200^[5]	ECO:0000314	direct assay evidence used in manual assertion		F	occurs_at:(SO:0001862)	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	PMID:16823372^[3]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:16823372^[3]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0003723	RNA binding	PMID:16043634^[2]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000077814 RGD:621107 RGD:621574	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:109263 MGI:MGI:1855672 PANTHER:PTN000077814	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:109263 PANTHER:PTN000077815	C		Seeded From UniProt	complete
enables	GO:0004521	endoribonuclease activity	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0033528 FB:FBgn0038327 PANTHER:PTN000077814	F		Seeded From UniProt	complete
enables	GO:0003697	single-stranded DNA binding	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000077814 RGD:621107 RGD:621574	F		Seeded From UniProt	complete
involved_in	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0004521	P		Seeded From UniProt	complete
enables	GO:0003697	single-stranded DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR033956	F		Seeded From UniProt	complete
enables	GO:0003723	RNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR033956	F		Seeded From UniProt	complete
involved_in	GO:0016070	RNA metabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR033956	P		Seeded From UniProt	complete
enables	GO:0043565	sequence-specific DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002848 InterPro:IPR016068 InterPro:IPR016069 InterPro:IPR036081	F		Seeded From UniProt	complete
involved_in	GO:0008033	tRNA processing	PMID:22773104^[7]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
NOT\|involved_in	GO:0006303	double-strand break repair via nonhomologous end joining	PMID:18062930^[1]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
NOT\|involved_in	GO:0000724	double-strand break repair via homologous recombination	PMID:18062930^[1]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F		Seeded From UniProt	complete
enables	GO:0003723	RNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0694	F		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
involved_in	GO:0051321	meiotic cell cycle	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0469	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Jaendling, A et al. (2008) Functional characterisation of the Schizosaccharomyces pombe homologue of the leukaemia-associated translocation breakpoint binding protein translin and its binding partner, TRAX. Biochim. Biophys. Acta 1783 203-13 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 Laufman, O et al. (2005) Cloning and characterization of the Schizosaccharomyces pombe homologs of the human protein Translin and the Translin-associated protein TRAX. Nucleic Acids Res. 33 4128-39 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 Matsuyama, A et al. (2006) ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat. Biotechnol. 24 841-7 PubMed GONUTS page
↑ Aslett, M & Wood, V (2006) Gene Ontology annotation status of the fission yeast genome: preliminary coverage approaches 100%. Yeast 23 913-9 PubMed GONUTS page
↑ ^5.0 ^5.1 Eliahoo, E et al. (2010) Mapping of interaction sites of the Schizosaccharomyces pombe protein Translin with nucleic acids and proteins: a combined molecular genetics and bioinformatics study. Nucleic Acids Res. 38 2975-89 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 ^6.3 ^6.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Li, L et al. (2012) The translin-TRAX complex (C3PO) is a ribonuclease in tRNA processing. Nat. Struct. Mol. Biol. 19 824-30 PubMed GONUTS page

[PMID:18062930-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 Jaendling, A et al. (2008) Functional characterisation of the Schizosaccharomyces pombe homologue of the leukaemia-associated translocation breakpoint binding protein translin and its binding partner, TRAX. Biochim. Biophys. Acta 1783 203-13 PubMed GONUTS page

[PMID:16043634-2] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 Laufman, O et al. (2005) Cloning and characterization of the Schizosaccharomyces pombe homologs of the human protein Translin and the Translin-associated protein TRAX. Nucleic Acids Res. 33 4128-39 PubMed GONUTS page

[PMID:16823372-3] 3.0 ^3.1 ^3.2 ^3.3 Matsuyama, A et al. (2006) ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat. Biotechnol. 24 841-7 PubMed GONUTS page

[PMID:17072883-4] Aslett, M & Wood, V (2006) Gene Ontology annotation status of the fission yeast genome: preliminary coverage approaches 100%. Yeast 23 913-9 PubMed GONUTS page

[PMID:20081200-5] 5.0 ^5.1 Eliahoo, E et al. (2010) Mapping of interaction sites of the Schizosaccharomyces pombe protein Translin with nucleic acids and proteins: a combined molecular genetics and bioinformatics study. Nucleic Acids Res. 38 2975-89 PubMed GONUTS page

[PMID:21873635-6] 6.0 ^6.1 ^6.2 ^6.3 ^6.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:22773104-7] Li, L et al. (2012) The translin-TRAX complex (C3PO) is a ribonuclease in tRNA processing. Nat. Struct. Mol. Biol. 19 824-30 PubMed GONUTS page

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SCHPO:TSN1

Contents

Annotations

Notes

References

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