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SALTY:SOPA

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Species (Taxon ID) Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720). (99287)
Gene Name(s) sopA
Protein Name(s) E3 ubiquitin-protein ligase SopA

Salmonella outer protein A Secreted effector protein SopA

External Links
UniProt Q8ZNR3
EMBL AE006468
RefSeq NP_461011.1
PDB 2QYU
2QZA
3SY2
PDBsum 2QYU
2QZA
3SY2
ProteinModelPortal Q8ZNR3
SMR Q8ZNR3
DIP DIP-46397N
STRING 99287.STM2066
PaxDb Q8ZNR3
PRIDE Q8ZNR3
EnsemblBacteria AAL20970
GeneID 1253587
KEGG stm:STM2066
PATRIC 32382715
eggNOG COG1357
HOGENOM HOG000071508
OMA YSQEKVR
OrthoDB EOG6BGNW5
BioCyc SENT99287:GCTI-2078-MONOMER
EvolutionaryTrace Q8ZNR3
Proteomes UP000001014
GO GO:0005576
GO:0043657
GO:0016874
GO:0004842
GO:0009405
GO:0016567
InterPro IPR001646
IPR025725
IPR025726
Pfam PF13599
PF13981
PF13979

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0009405

pathogenesis

PMID:19762438[1]

ECO:0000270

P

Increased SopA expression in the high osmolarity of the intestinal environment supporting pathogenicity beyond the stomach organ (fig. 3b).

complete

involved_in

GO:0016567

protein ubiquitination

PMID:17076670[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009405

pathogenesis

PMID:17076670[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9S4P4

C

Seeded From UniProt

complete

enables

GO:0004842

ubiquitin-protein transferase activity

PMID:17076670[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0004842

ubiquitin-protein transferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR025725

F

Seeded From UniProt

complete

involved_in

GO:0016567

protein ubiquitination

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR025725

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

involved_in

GO:0009405

pathogenesis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0843

P

Seeded From UniProt

complete

part_of

GO:0043657

host cell

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0427

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Gong, H et al. (2010) Differential expression of Salmonella type III secretion system factors InvJ, PrgJ, SipC, SipD, SopA and SopB in cultures and in mice. Microbiology (Reading, Engl.) 156 116-27 PubMed GONUTS page
  2. 2.0 2.1 2.2 Zhang, Y et al. (2006) The inflammation-associated Salmonella SopA is a HECT-like E3 ubiquitin ligase. Mol. Microbiol. 62 786-93 PubMed GONUTS page