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RAT:SOSD1

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Species (Taxon ID) Rattus norvegicus (Rat). (10116)
Gene Name(s) Sostdc1 (synonyms: Usag1, Wise)
Protein Name(s) Sclerostin domain-containing protein 1

Uterine sensitization-associated gene 1 protein USAG-1 Wnt-signaling modulator

External Links
UniProt Q642G2
EMBL AF411056
BC081710
RefSeq NP_714959.1
UniGene Rn.2415
STRING 10116.ENSRNOP00000008106
PaxDb Q642G2
Ensembl ENSRNOT00000008106
GeneID 266803
KEGG rno:266803
UCSC RGD:628877
CTD 25928
RGD 628877
eggNOG NOG47771
GeneTree ENSGT00390000014900
HOGENOM HOG000252934
HOVERGEN HBG003729
InParanoid Q642G2
OMA AKPAQHH
OrthoDB EOG7CVPZN
PhylomeDB Q642G2
TreeFam TF353019
NextBio 624707
PRO PR:Q642G2
Proteomes UP000002494
Genevestigator Q642G2
GO GO:0005615
GO:0007566
GO:0031069
GO:0060648
GO:0030514
GO:0090090
GO:0010454
GO:0042475
GO:0007389
GO:0016055
InterPro IPR006207
IPR008835
PANTHER PTHR14903
Pfam PF05463
PROSITE PS01225

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0030513

positive regulation of BMP signaling pathway

PMID:17460719[1]

ECO:0000314

P

Fig 1. shows a statistically significant improvement in the incidence of bony union when administration of the Ad.BMP-2 was delayed

complete
CACAO 5602

involved_in

GO:0007566

embryo implantation

PMID:12390898[2]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0030509

BMP signaling pathway

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0098821

P

Seeded From UniProt

complete

involved_in

GO:2000016

negative regulation of determination of dorsal identity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6X4U4
ensembl:ENSP00000304930

P

Seeded From UniProt

complete

enables

GO:0098821

BMP receptor activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6X4U4
ensembl:ENSP00000304930

F

Seeded From UniProt

complete

involved_in

GO:0045662

negative regulation of myoblast differentiation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6X4U4
ensembl:ENSP00000304930

P

Seeded From UniProt

complete

enables

GO:0036122

BMP binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6X4U4
ensembl:ENSP00000304930

F

Seeded From UniProt

complete

involved_in

GO:0030514

negative regulation of BMP signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6X4U4
ensembl:ENSP00000304930

P

Seeded From UniProt

complete

involved_in

GO:0030178

negative regulation of Wnt signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6X4U4
ensembl:ENSP00000304930

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6X4U4
ensembl:ENSP00000304930

C

Seeded From UniProt

complete

involved_in

GO:0090090

negative regulation of canonical Wnt signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9CQN4
ensembl:ENSMUSP00000040230

P

Seeded From UniProt

complete

involved_in

GO:0060648

mammary gland bud morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9CQN4
ensembl:ENSMUSP00000040230

P

Seeded From UniProt

complete

involved_in

GO:0042475

odontogenesis of dentin-containing tooth

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9CQN4
ensembl:ENSMUSP00000040230

P

Seeded From UniProt

complete

involved_in

GO:0031069

hair follicle morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9CQN4
ensembl:ENSMUSP00000040230

P

Seeded From UniProt

complete

involved_in

GO:0030514

negative regulation of BMP signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9CQN4
ensembl:ENSMUSP00000040230

P

Seeded From UniProt

complete

involved_in

GO:0010454

negative regulation of cell fate commitment

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9CQN4
ensembl:ENSMUSP00000040230

P

Seeded From UniProt

complete

involved_in

GO:0007389

pattern specification process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9CQN4
ensembl:ENSMUSP00000040230

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9CQN4
ensembl:ENSMUSP00000040230

C

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008835

C

Seeded From UniProt

complete

involved_in

GO:0016055

Wnt signaling pathway

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0879

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Betz, OB et al. (2007) Delayed administration of adenoviral BMP-2 vector improves the formation of bone in osseous defects. Gene Ther. 14 1039-44 PubMed GONUTS page
  2. Simmons, DG & Kennedy, TG (2002) Uterine sensitization-associated gene-1: a novel gene induced within the rat endometrium at the time of uterine receptivity/sensitization for the decidual cell reaction. Biol. Reprod. 67 1638-45 PubMed GONUTS page