RAT:SHAN1

Species (Taxon ID)	Rattus norvegicus (Rat). (10116)
Gene Name(s)	Shank1
Protein Name(s)	SH3 and multiple ankyrin repeat domains protein 1 Shank1 GKAP/SAPAP-interacting protein SPANK-1 Somatostatin receptor-interacting protein SSTR-interacting protein SSTRIP Synamon
External Links
UniProt	Q9WV48
EMBL	AF102855 AF131951 AF159046 AF141904
RefSeq	NP_113939.2 XP_008757636.1 XP_008757637.1 XP_008757639.1
UniGene	Rn.225968
PDB	1Q3O 1Q3P 3L4F 3QJM 3QJN
PDBsum	1Q3O 1Q3P 3L4F 3QJM 3QJN
ProteinModelPortal	Q9WV48
SMR	Q9WV48
BioGrid	249365
IntAct	Q9WV48
MINT	MINT-101286
PhosphoSite	Q9WV48
PaxDb	Q9WV48
PRIDE	Q9WV48
Ensembl	ENSRNOT00000026100 ENSRNOT00000044257 ENSRNOT00000048805 ENSRNOT00000049346
GeneID	78957
KEGG	rno:78957
UCSC	RGD:621011
CTD	50944
RGD	621011
eggNOG	COG0666
GeneTree	ENSGT00510000046474
HOGENOM	HOG000293276
HOVERGEN	HBG079186
InParanoid	Q9WV48
KO	K15009
OMA	WEEGPGP
OrthoDB	EOG7X6KZ7
PhylomeDB	Q9WV48
EvolutionaryTrace	Q9WV48
NextBio	614372
PRO	PR:Q9WV48
Proteomes	UP000002494
ExpressionAtlas	Q9WV48
Genevestigator	Q9WV48
GO	GO:0030054 GO:0005737 GO:0030425 GO:0043197 GO:0060076 GO:0005622 GO:0008328 GO:0043005 GO:0097481 GO:0005886 GO:0045211 GO:0045202 GO:0071532 GO:0030160 GO:0042802 GO:0035255 GO:0008022 GO:0032403 GO:0030159 GO:0097110 GO:0017124 GO:0031877 GO:0030534 GO:0008306 GO:0007016 GO:0060997 GO:0050894 GO:0046959 GO:0007616 GO:0032232 GO:0050885 GO:0042048 GO:0060999 GO:2000463 GO:0006461 GO:0035418 GO:2000311 GO:0060013 GO:0035176 GO:0060074 GO:0071625
Gene3D	1.10.150.50 1.25.40.20 2.30.42.10
InterPro	IPR002110 IPR020683 IPR001478 IPR001660 IPR013761 IPR021129 IPR011511 IPR001452
Pfam	PF12796 PF00595 PF00536 PF07653
SMART	SM00248 SM00228 SM00454 SM00326
SUPFAM	SSF47769 SSF48403 SSF50044 SSF50156
PROSITE	PS50297 PS50088 PS50106 PS50105 PS50002

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:2000463	positive regulation of excitatory postsynaptic potential	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:D3YZU1	P	Seeded From UniProt	complete
involved_in	GO:2000311	regulation of AMPA receptor activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:D3YZU1	P	Seeded From UniProt	complete
part_of	GO:0014069	postsynaptic density	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:D3YZU1	C	Seeded From UniProt	complete
enables	GO:0097110	scaffold protein binding	PMID:10433269^[1]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q9Z214	F	Seeded From UniProt	complete
enables	GO:0071532	ankyrin repeat binding	PMID:15496675^[2]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q9WV48	F	Seeded From UniProt	complete
involved_in	GO:0060997	dendritic spine morphogenesis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:D3YZU1	P	Seeded From UniProt	complete
part_of	GO:0060076	excitatory synapse	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:D3YZU1	C	Seeded From UniProt	complete
involved_in	GO:0060013	righting reflex	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:D3YZU1	P	Seeded From UniProt	complete
involved_in	GO:0050885	neuromuscular process controlling balance	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:D3YZU1	P	Seeded From UniProt	complete
involved_in	GO:0046959	habituation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:D3YZU1	P	Seeded From UniProt	complete
part_of	GO:0045202	synapse	PMID:15496675^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0043197	dendritic spine	PMID:15496675^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:D3YZU1	C	Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	PMID:15496675^[2]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q9WV48	F	Seeded From UniProt	complete
involved_in	GO:0042048	olfactory behavior	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:D3YZU1	P	Seeded From UniProt	complete
involved_in	GO:0035418	protein localization to synapse	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:D3YZU1	P	Seeded From UniProt	complete
involved_in	GO:0032232	negative regulation of actin filament bundle assembly	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:D3YZU1	P	Seeded From UniProt	complete
enables	GO:0030160	GKAP/Homer scaffold activity	PMID:10433269^[1]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
colocalizes_with	GO:0017146	NMDA selective glutamate receptor complex	PMID:10433269^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
enables	GO:0017124	SH3 domain binding	PMID:15496675^[2]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q9WV48	F	Seeded From UniProt	complete
colocalizes_with	GO:0008328	ionotropic glutamate receptor complex	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:D3YZU1	C	Seeded From UniProt	complete
involved_in	GO:0008306	associative learning	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:D3YZU1	P	Seeded From UniProt	complete
involved_in	GO:0007616	long-term memory	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:D3YZU1	P	Seeded From UniProt	complete
involved_in	GO:0065003	protein-containing complex assembly	PMID:10433269^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:D3YZU1	C	Seeded From UniProt	complete
involved_in	GO:0060999	positive regulation of dendritic spine development	PMID:18287537^[3]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0060074	synapse maturation	PMID:18287537^[3]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0031877	somatostatin receptor binding	PMID:10551867^[4]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P30680	F	Seeded From UniProt	complete
part_of	GO:0030425	dendrite	PMID:10551867^[4]	ECO:0000303	author statement without traceable support used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0007016	cytoskeletal anchoring at plasma membrane	PMID:10551867^[4]	ECO:0000303	author statement without traceable support used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0045211	postsynaptic membrane	PMID:10958799^[5]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
enables	GO:0044877	protein-containing complex binding	PMID:11178875^[6]	ECO:0000353	physical interaction evidence used in manual assertion	RGD:620223 RGD:621667 RGD:631353 RGD:68424	F	Seeded From UniProt	complete
enables	GO:0035255	ionotropic glutamate receptor binding	PMID:20171009^[7]	ECO:0000353	physical interaction evidence used in manual assertion	RGD:2738	F	Seeded From UniProt	complete
enables	GO:0030159	receptor signaling complex scaffold activity	PMID:10958799^[5]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
enables	GO:0008022	protein C-terminus binding	PMID:10958799^[5]	ECO:0000353	physical interaction evidence used in manual assertion	RGD:620768	F	Seeded From UniProt	complete
involved_in	GO:2000463	positive regulation of excitatory postsynaptic potential	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 MGI:MGI:3613677 PANTHER:PTN001191880	P	Seeded From UniProt	complete
involved_in	GO:2000311	regulation of AMPA receptor activity	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:3613677 PANTHER:PTN001191880	P	Seeded From UniProt	complete
involved_in	GO:0097107	postsynaptic density assembly	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 PANTHER:PTN001191880	P	Seeded From UniProt	complete
involved_in	GO:0060999	positive regulation of dendritic spine development	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 PANTHER:PTN001191880 RGD:621011	P	Seeded From UniProt	complete
involved_in	GO:0060997	dendritic spine morphogenesis	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 MGI:MGI:3613677 PANTHER:PTN001191880	P	Seeded From UniProt	complete
involved_in	GO:0060291	long-term synaptic potentiation	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 MGI:MGI:2671987 PANTHER:PTN001191880	P	Seeded From UniProt	complete
involved_in	GO:0051968	positive regulation of synaptic transmission, glutamatergic	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 MGI:MGI:2671987 PANTHER:PTN001191880	P	Seeded From UniProt	complete
involved_in	GO:0051124	synaptic growth at neuromuscular junction	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0040752 PANTHER:PTN001191880	P	Seeded From UniProt	complete
involved_in	GO:0048854	brain morphogenesis	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 PANTHER:PTN001191880 ZFIN:ZDB-GENE-060503-369	P	Seeded From UniProt	complete
colocalizes_with	GO:0045211	postsynaptic membrane	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2671987 MGI:MGI:3613677 PANTHER:PTN001191880 RGD:621011	C	Seeded From UniProt	complete
part_of	GO:0044309	neuron spine	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 PANTHER:PTN001191880	C	Seeded From UniProt	complete
part_of	GO:0043197	dendritic spine	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2671987 MGI:MGI:3613677 PANTHER:PTN001191880 RGD:621011	C	Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 MGI:MGI:2671987 MGI:MGI:3613677 PANTHER:PTN001191880	C	Seeded From UniProt	complete
enables	GO:0035255	ionotropic glutamate receptor binding	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 MGI:MGI:2671987 MGI:MGI:3613677 PANTHER:PTN001191878 RGD:621011	F	Seeded From UniProt	complete
part_of	GO:0030425	dendrite	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:3613677 PANTHER:PTN001191880	C	Seeded From UniProt	complete
enables	GO:0030160	GKAP/Homer scaffold activity	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:3613677 PANTHER:PTN001191878 RGD:621011 RGD:69264	F	Seeded From UniProt	complete
enables	GO:0030159	receptor signaling complex scaffold activity	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001191878 RGD:621011	F	Seeded From UniProt	complete
part_of	GO:0014069	postsynaptic density	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0040752 MGI:MGI:3613677 PANTHER:PTN001191880 RGD:628772 RGD:69264	C	Seeded From UniProt	complete
colocalizes_with	GO:0008328	ionotropic glutamate receptor complex	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2671987 MGI:MGI:3613677 PANTHER:PTN001191878	C	Seeded From UniProt	complete
involved_in	GO:0007416	synapse assembly	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 MGI:MGI:2671987 PANTHER:PTN001191880	P	Seeded From UniProt	complete
involved_in	GO:2000463	positive regulation of excitatory postsynaptic potential	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3YZU1 ensembl:ENSMUSP00000103571	P	Seeded From UniProt	complete
involved_in	GO:2000311	regulation of AMPA receptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3YZU1 ensembl:ENSMUSP00000103571	P	Seeded From UniProt	complete
involved_in	GO:0099173	postsynapse organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3YZU1 ensembl:ENSMUSP00000103571	P	Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3YZU1 ensembl:ENSMUSP00000103571	C	Seeded From UniProt	complete
part_of	GO:0098685	Schaffer collateral - CA1 synapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3YZU1 ensembl:ENSMUSP00000103571	C	Seeded From UniProt	complete
involved_in	GO:0071625	vocalization behavior	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3YZU1 ensembl:ENSMUSP00000103571	P	Seeded From UniProt	complete
involved_in	GO:0060997	dendritic spine morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3YZU1 ensembl:ENSMUSP00000103571	P	Seeded From UniProt	complete
part_of	GO:0060076	excitatory synapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3YZU1 ensembl:ENSMUSP00000103571	C	Seeded From UniProt	complete
involved_in	GO:0060013	righting reflex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3YZU1 ensembl:ENSMUSP00000103571	P	Seeded From UniProt	complete
involved_in	GO:0050885	neuromuscular process controlling balance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3YZU1 ensembl:ENSMUSP00000103571	P	Seeded From UniProt	complete
involved_in	GO:0046959	habituation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3YZU1 ensembl:ENSMUSP00000103571	P	Seeded From UniProt	complete
part_of	GO:0045211	postsynaptic membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3YZU1 ensembl:ENSMUSP00000103571	C	Seeded From UniProt	complete
part_of	GO:0043197	dendritic spine	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3YZU1 ensembl:ENSMUSP00000103571	C	Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3YZU1 ensembl:ENSMUSP00000103571	C	Seeded From UniProt	complete
involved_in	GO:0042048	olfactory behavior	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3YZU1 ensembl:ENSMUSP00000103571	P	Seeded From UniProt	complete
involved_in	GO:0035418	protein localization to synapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3YZU1 ensembl:ENSMUSP00000103571	P	Seeded From UniProt	complete
enables	GO:0035255	ionotropic glutamate receptor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3YZU1 ensembl:ENSMUSP00000103571	F	Seeded From UniProt	complete
involved_in	GO:0035176	social behavior	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3YZU1 ensembl:ENSMUSP00000103571	P	Seeded From UniProt	complete
involved_in	GO:0032232	negative regulation of actin filament bundle assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3YZU1 ensembl:ENSMUSP00000103571	P	Seeded From UniProt	complete
part_of	GO:0030425	dendrite	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3YZU1 ensembl:ENSMUSP00000103571	C	Seeded From UniProt	complete
enables	GO:0030160	GKAP/Homer scaffold activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3YZU1 ensembl:ENSMUSP00000103571	F	Seeded From UniProt	complete
part_of	GO:0014069	postsynaptic density	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3YZU1 ensembl:ENSMUSP00000103571	C	Seeded From UniProt	complete
part_of	GO:0008328	ionotropic glutamate receptor complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3YZU1 ensembl:ENSMUSP00000103571	C	Seeded From UniProt	complete
involved_in	GO:0008306	associative learning	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3YZU1 ensembl:ENSMUSP00000103571	P	Seeded From UniProt	complete
involved_in	GO:0007616	long-term memory	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3YZU1 ensembl:ENSMUSP00000103571	P	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:D3YZU1 ensembl:ENSMUSP00000103571	C	Seeded From UniProt	complete
involved_in	GO:0071625	vocalization behavior	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Y566 ensembl:ENSP00000293441	P	Seeded From UniProt	complete
involved_in	GO:0050894	determination of affect	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Y566 ensembl:ENSP00000293441	P	Seeded From UniProt	complete
involved_in	GO:0035176	social behavior	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Y566 ensembl:ENSP00000293441	P	Seeded From UniProt	complete
involved_in	GO:0030534	adult behavior	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Y566 ensembl:ENSP00000293441	P	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Y566 ensembl:ENSP00000293441	C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9Y566 ensembl:ENSP00000293441	C	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	Reactome:R-RNO-6794350 Reactome:R-RNO-6794341	ECO:0000304	author statement supported by traceable reference used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0030054	cell junction	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0965	C	Seeded From UniProt	complete
part_of	GO:0045211	postsynaptic membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0628	C	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C	Seeded From UniProt	complete
involved_in	GO:0007399	nervous system development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0524	P	Seeded From UniProt	complete
involved_in	GO:0030154	cell differentiation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0221	P	Seeded From UniProt	complete
part_of	GO:0045202	synapse	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0770 UniProtKB-SubCell:SL-0258	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003	C	Seeded From UniProt	complete
part_of	GO:0014069	postsynaptic density	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0297	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 Tu, JC et al. (1999) Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins. Neuron 23 583-92 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 Romorini, S et al. (2004) A functional role of postsynaptic density-95-guanylate kinase-associated protein complex in regulating Shank assembly and stability to synapses. J. Neurosci. 24 9391-404 PubMed GONUTS page
↑ ^3.0 ^3.1 Arstikaitis, P et al. (2008) Paralemmin-1, a modulator of filopodia induction is required for spine maturation. Mol. Biol. Cell 19 2026-38 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 Zitzer, H et al. (1999) Somatostatin receptor interacting protein defines a novel family of multidomain proteins present in human and rodent brain. J. Biol. Chem. 274 32997-3001 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 Tobaben, S et al. (2000) The G protein-coupled receptor CL1 interacts directly with proteins of the Shank family. J. Biol. Chem. 275 36204-10 PubMed GONUTS page
↑ Lim, S et al. (2001) Sharpin, a novel postsynaptic density protein that directly interacts with the shank family of proteins. Mol. Cell. Neurosci. 17 385-97 PubMed GONUTS page
↑ Miletic, G et al. (2010) Loose ligation of the rat sciatic nerve elicits early accumulation of Shank1 protein in the post-synaptic density of spinal dorsal horn neurons. Pain 149 152-9 PubMed GONUTS page
↑ ^8.00 ^8.01 ^8.02 ^8.03 ^8.04 ^8.05 ^8.06 ^8.07 ^8.08 ^8.09 ^8.10 ^8.11 ^8.12 ^8.13 ^8.14 ^8.15 ^8.16 ^8.17 ^8.18 ^8.19 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:10433269-1] 1.0 ^1.1 ^1.2 ^1.3 Tu, JC et al. (1999) Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins. Neuron 23 583-92 PubMed GONUTS page

[PMID:15496675-2] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 Romorini, S et al. (2004) A functional role of postsynaptic density-95-guanylate kinase-associated protein complex in regulating Shank assembly and stability to synapses. J. Neurosci. 24 9391-404 PubMed GONUTS page

[PMID:18287537-3] 3.0 ^3.1 Arstikaitis, P et al. (2008) Paralemmin-1, a modulator of filopodia induction is required for spine maturation. Mol. Biol. Cell 19 2026-38 PubMed GONUTS page

[PMID:10551867-4] 4.0 ^4.1 ^4.2 Zitzer, H et al. (1999) Somatostatin receptor interacting protein defines a novel family of multidomain proteins present in human and rodent brain. J. Biol. Chem. 274 32997-3001 PubMed GONUTS page

[PMID:10958799-5] 5.0 ^5.1 ^5.2 Tobaben, S et al. (2000) The G protein-coupled receptor CL1 interacts directly with proteins of the Shank family. J. Biol. Chem. 275 36204-10 PubMed GONUTS page

[PMID:11178875-6] Lim, S et al. (2001) Sharpin, a novel postsynaptic density protein that directly interacts with the shank family of proteins. Mol. Cell. Neurosci. 17 385-97 PubMed GONUTS page

[PMID:20171009-7] Miletic, G et al. (2010) Loose ligation of the rat sciatic nerve elicits early accumulation of Shank1 protein in the post-synaptic density of spinal dorsal horn neurons. Pain 149 152-9 PubMed GONUTS page

[PMID:21873635-8] 8.00 ^8.01 ^8.02 ^8.03 ^8.04 ^8.05 ^8.06 ^8.07 ^8.08 ^8.09 ^8.10 ^8.11 ^8.12 ^8.13 ^8.14 ^8.15 ^8.16 ^8.17 ^8.18 ^8.19 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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RAT:SHAN1

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