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RAT:MANEA
Contents
| Species (Taxon ID) | Rattus norvegicus (Rat). (10116) | |
| Gene Name(s) | Manea | |
| Protein Name(s) | Glycoprotein endo-alpha-1,2-mannosidase
Endo-alpha mannosidase Endomannosidase rEndo Endo-alpha-D-mannosidase Enman | |
| External Links | ||
| UniProt | Q5GF25 | |
| EMBL | AF023657 AY599499 | |
| RefSeq | NP_542963.2 XP_006238022.1 XP_006238023.1 | |
| UniGene | Rn.10855 | |
| MINT | MINT-4566608 | |
| CAZy | GH99 | |
| PaxDb | Q5GF25 | |
| PRIDE | Q5GF25 | |
| Ensembl | ENSRNOT00000011576 | |
| GeneID | 140808 | |
| KEGG | rno:140808 | |
| UCSC | RGD:620327 | |
| CTD | 79694 | |
| RGD | 620327 | |
| eggNOG | NOG84309 | |
| GeneTree | ENSGT00390000016054 | |
| HOGENOM | HOG000223388 | |
| HOVERGEN | HBG103563 | |
| InParanoid | Q5GF25 | |
| KO | K15538 | |
| OMA | IETHMKQ | |
| OrthoDB | EOG7NGQB6 | |
| PhylomeDB | Q5GF25 | |
| TreeFam | TF324051 | |
| BRENDA | 3.2.1.130 | |
| Reactome | REACT_199031 | |
| NextBio | 620723 | |
| PRO | PR:Q5GF25 | |
| Proteomes | UP000002494 | |
| Genevestigator | Q5GF25 | |
| GO | GO:0000139 GO:0016021 GO:0004559 GO:0004569 GO:0008152 | |
| InterPro | IPR026071 | |
| PANTHER | PTHR13572 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0000139 |
Golgi membrane |
ECO:0000314 |
C |
FIG. 8. Comparison of endomannosidase activity in Golgi, RER, and total microsomal (Micro) fractions from rat liver. |
complete | |||||
| GO:0030134 |
ER to Golgi transport vesicle |
ECO:0000314 |
C |
Fig. 1. Recombinant rat endomannosidase is localized in the Golgi apparatus. Immunogold labeling for myc-tagged rEndo in the cis- and medial-Golgi cisternae and in transport vesicles. |
complete | |||||
| GO:0005797 |
Golgi medial cisterna |
ECO:0000314 |
C |
Fig. 1. Recombinant rat endomannosidase is localized in the Golgi apparatus. Immunogold labeling for myc-tagged rEndo in the cis- and medial-Golgi cisternae and in transport vesicles. |
complete | |||||
| GO:0000138 |
Golgi trans cisterna |
ECO:0000314 |
C |
Fig. 1. Recombinant rat endomannosidase is localized in the Golgi apparatus. Immunogold labeling for myc-tagged rEndo in the cis- and medial-Golgi cisternae and in transport vesicles. |
complete | |||||
| GO:0006491 |
N-glycan processing |
ECO:0000314 |
P |
FIG. 4. Comparison of processing by endomannosidase of glycopeptides and their corresponding free oligosaccharides released by endo H digestion. |
complete | |||||
| GO:0004559 |
alpha-mannosidase activity |
ECO:0000314 |
F |
complete | ||||||
|
enables |
GO:0004559 |
alpha-mannosidase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000339726 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004559 |
alpha-mannosidase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000339726 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q5SRI9 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016798 |
hydrolase activity, acting on glycosyl bonds |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004569 |
glycoprotein endo-alpha-1,2-mannosidase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0000139 |
Golgi membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Lubas, WA & Spiro, RG (1987) Golgi endo-alpha-D-mannosidase from rat liver, a novel N-linked carbohydrate unit processing enzyme. J. Biol. Chem. 262 3775-81 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Torossi, T et al. (2010) Endomannosidase undergoes phosphorylation in the Golgi apparatus. Glycobiology 20 55-61 PubMed GONUTS page
- ↑ Lubas, WA & Spiro, RG (1988) Evaluation of the role of rat liver Golgi endo-alpha-D-mannosidase in processing N-linked oligosaccharides. J. Biol. Chem. 263 3990-8 PubMed GONUTS page
- ↑ 4.0 4.1 Spiro, MJ et al. (1997) Molecular cloning and expression of rat liver endo-alpha-mannosidase, an N-linked oligosaccharide processing enzyme. J. Biol. Chem. 272 29356-63 PubMed GONUTS page
- ↑ 5.0 5.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
