RAT:MA2A1

Species (Taxon ID)	Rattus norvegicus (Rat). (10116)
Gene Name(s)	Man2a1 (synonyms: Mana2)
Protein Name(s)	Alpha-mannosidase 2 Golgi alpha-mannosidase II AMan II Man II Mannosidase alpha class 2A member 1 Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase
External Links
UniProt	P28494
EMBL	AABR06062074 AABR06062075 CH473997 M24353
PIR	A33901
RefSeq	NP_037111.2
UniGene	Rn.163804
ProteinModelPortal	P28494
IntAct	P28494
MINT	MINT-4574652
STRING	10116.ENSRNOP00000020767
ChEMBL	CHEMBL2257
CAZy	GH38
PhosphoSite	P28494
PaxDb	P28494
PRIDE	P28494
Ensembl	ENSRNOT00000020767
GeneID	25478
KEGG	rno:25478
UCSC	RGD:3038
RGD	3038
eggNOG	COG0383
GeneTree	ENSGT00510000046304
HOGENOM	HOG000293253
HOVERGEN	HBG052390
InParanoid	P28494
KO	K01231
OMA	FFEHVTH
Reactome	REACT_199013
UniPathway	UPA00378
NextBio	606801
PRO	PR:P28494
Proteomes	UP000002494
Genevestigator	P28494
GO	GO:0000139 GO:0016021 GO:0030246 GO:0004572 GO:0008270 GO:0006013 GO:0006486
Gene3D	1.20.1270.50 2.60.40.1180 3.20.110.10
InterPro	IPR011013 IPR011330 IPR013780 IPR027291 IPR011682 IPR015341 IPR000602 IPR028995
Pfam	PF09261 PF01074 PF07748
SMART	SM00872
SUPFAM	SSF74650 SSF88688 SSF88713

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0006517	protein deglycosylation	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0011740 FB:FBgn0026616 PANTHER:PTN002480870	P	Seeded From UniProt	complete
involved_in	GO:0006491	N-glycan processing	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0011740 FB:FBgn0026616 MGI:MGI:104669 PANTHER:PTN000176398	P	Seeded From UniProt	complete
involved_in	GO:0006013	mannose metabolic process	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:107286 PANTHER:PTN002480870 RGD:1308840	P	Seeded From UniProt	complete
enables	GO:0004559	alpha-mannosidase activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0027611 MGI:MGI:107286 PANTHER:PTN002480870 RGD:1308840 RGD:3039 TAIR:locus:2147855 UniProtKB:P94078 dictyBase:DDB_G0292206	F	Seeded From UniProt	complete
part_of	GO:0000139	Golgi membrane	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:104669 PANTHER:PTN000176398	C	Seeded From UniProt	complete
involved_in	GO:0060042	retina morphogenesis in camera-type eye	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27046 ensembl:ENSMUSP00000083928	P	Seeded From UniProt	complete
involved_in	GO:0050769	positive regulation of neurogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27046 ensembl:ENSMUSP00000083928	P	Seeded From UniProt	complete
involved_in	GO:0048286	lung alveolus development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27046 ensembl:ENSMUSP00000083928	P	Seeded From UniProt	complete
enables	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27046 ensembl:ENSMUSP00000083928	F	Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27046 ensembl:ENSMUSP00000083928	F	Seeded From UniProt	complete
enables	GO:0015923	mannosidase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27046 ensembl:ENSMUSP00000083928	F	Seeded From UniProt	complete
involved_in	GO:0007585	respiratory gaseous exchange	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27046 ensembl:ENSMUSP00000083928	P	Seeded From UniProt	complete
involved_in	GO:0007033	vacuole organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27046 ensembl:ENSMUSP00000083928	P	Seeded From UniProt	complete
involved_in	GO:0007005	mitochondrion organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27046 ensembl:ENSMUSP00000083928	P	Seeded From UniProt	complete
involved_in	GO:0006491	N-glycan processing	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27046 ensembl:ENSMUSP00000083928	P	Seeded From UniProt	complete
part_of	GO:0005801	cis-Golgi network	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27046 ensembl:ENSMUSP00000083928	C	Seeded From UniProt	complete
part_of	GO:0005794	Golgi apparatus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27046 ensembl:ENSMUSP00000083928	C	Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27046 ensembl:ENSMUSP00000083928	C	Seeded From UniProt	complete
involved_in	GO:0001889	liver development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27046 ensembl:ENSMUSP00000083928	P	Seeded From UniProt	complete
involved_in	GO:0001701	in utero embryonic development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27046 ensembl:ENSMUSP00000083928	P	Seeded From UniProt	complete
part_of	GO:0000139	Golgi membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P27046 ensembl:ENSMUSP00000083928	C	Seeded From UniProt	complete
part_of	GO:0005797	Golgi medial cisterna	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q16706 ensembl:ENSP00000261483	C	Seeded From UniProt	complete
enables	GO:0003824	catalytic activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011013 InterPro:IPR011330	F	Seeded From UniProt	complete
enables	GO:0004559	alpha-mannosidase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000602 InterPro:IPR011682 InterPro:IPR015341 InterPro:IPR037094	F	Seeded From UniProt	complete
involved_in	GO:0005975	carbohydrate metabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011013 InterPro:IPR011330	P	Seeded From UniProt	complete
involved_in	GO:0006013	mannose metabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000602 InterPro:IPR011682 InterPro:IPR015341 InterPro:IPR037094	P	Seeded From UniProt	complete
enables	GO:0030246	carbohydrate binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011013	F	Seeded From UniProt	complete
enables	GO:0004572	mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:3.2.1.114	F	Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F	Seeded From UniProt	complete
part_of	GO:0005794	Golgi apparatus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0333	C	Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C	Seeded From UniProt	complete
involved_in	GO:0008152	metabolic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0326	P	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C	Seeded From UniProt	complete
enables	GO:0016798	hydrolase activity, acting on glycosyl bonds	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0326	F	Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F	Seeded From UniProt	complete
part_of	GO:0000139	Golgi membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0134	C	Seeded From UniProt	complete
involved_in	GO:0006486	protein glycosylation	GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniPathway:UPA00378	P	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:21873635-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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RAT:MA2A1

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Notes

References

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