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RAT:IL17
Contents
| Species (Taxon ID) | Rattus norvegicus (Rat). (10116) | |
| Gene Name(s) | Il17a (synonyms: Ctla8, Il17) | |
| Protein Name(s) | Interleukin-17A
IL-17 IL-17A Cytotoxic T-lymphocyte-associated antigen 8 CTLA-8 | |
| External Links | ||
| UniProt | Q61453 | |
| EMBL | L13839 | |
| UniGene | Rn.218513 | |
| ProteinModelPortal | Q61453 | |
| STRING | 10116.ENSRNOP00000016664 | |
| PRIDE | Q61453 | |
| RGD | 2888 | |
| eggNOG | NOG42989 | |
| HOGENOM | HOG000064520 | |
| HOVERGEN | HBG006143 | |
| InParanoid | Q61453 | |
| PhylomeDB | Q61453 | |
| Proteomes | UP000002494 | |
| Genevestigator | Q61453 | |
| GO | GO:0005737 GO:0005615 GO:0005125 GO:0071385 GO:0006954 GO:0010940 GO:0045944 GO:0043200 | |
| Gene3D | 2.10.90.10 | |
| InterPro | IPR029034 IPR020440 IPR010345 | |
| PANTHER | PTHR21295 | |
| Pfam | PF06083 | |
| PRINTS | PR01932 | |
| SUPFAM | SSF57501 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0071385 |
cellular response to glucocorticoid stimulus |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045944 |
positive regulation of transcription by RNA polymerase II |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0043200 |
response to amino acid |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0010940 |
positive regulation of necrotic cell death |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005615 |
extracellular space |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003674 |
molecular_function |
ECO:0000307 |
no biological data found used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0005125 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0005125 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005125 |
cytokine activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006954 |
inflammatory response |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005615 |
extracellular space |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005125 |
cytokine activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Miljković, Z et al. (2009) Methylprednisolone inhibits IFN-gamma and IL-17 expression and production by cells infiltrating central nervous system in experimental autoimmune encephalomyelitis. J Neuroinflammation 6 37 PubMed GONUTS page
- ↑ 2.0 2.1 Ni, J et al. (2013) Involvement of interleukin-17A in pancreatic damage in rat experimental acute necrotizing pancreatitis. Inflammation 36 53-65 PubMed GONUTS page
- ↑ Yeh, CL et al. (2012) Effects of supplemental dietary arginine on the exogenous advanced glycosylation end product-induced interleukin-23/interleukin-17 immune response in rats. Nutrition 28 1063-7 PubMed GONUTS page
- ↑ Hu, MH et al. (2014) Neuroprotection effect of interleukin (IL)-17 secreted by reactive astrocytes is emerged from a high-level IL-17-containing environment during acute neuroinflammation. Clin. Exp. Immunol. 175 268-84 PubMed GONUTS page
- ↑ Xie, XJ et al. (2010) Th17 promotes acute rejection following liver transplantation in rats. J Zhejiang Univ Sci B 11 819-27 PubMed GONUTS page
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