GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

RAT:GABR2

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Rattus norvegicus (Rat). (10116)
Gene Name(s) Gabbr2 (synonyms: Gpr51)
Protein Name(s) Gamma-aminobutyric acid type B receptor subunit 2

GABA-B receptor 2 GABA-B-R2 GABA-BR2 GABABR2 Gb2 G-protein coupled receptor 51

External Links
UniProt O88871
EMBL AF074482
AJ011318
AF058795
AF109405
RefSeq NP_113990.1
UniGene Rn.162814
ProteinModelPortal O88871
BioGrid 249797
IntAct O88871
MINT MINT-1889821
BindingDB O88871
ChEMBL CHEMBL2111474
GuidetoPHARMACOLOGY 241
PhosphoSite O88871
PaxDb O88871
PRIDE O88871
GeneID 83633
KEGG rno:83633
UCSC RGD:619864
CTD 9568
RGD 619864
eggNOG NOG273984
HOGENOM HOG000112688
HOVERGEN HBG080355
InParanoid O88871
KO K04615
PhylomeDB O88871
TreeFam TF313965
NextBio 616227
PRO PR:O88871
Proteomes UP000002494
Genevestigator O88871
GO GO:0030054
GO:0038039
GO:0016021
GO:0005887
GO:0045211
GO:0004965
GO:0007214
InterPro IPR001828
IPR002455
IPR000337
IPR017978
IPR017979
IPR002457
IPR028082
PANTHER PTHR10519
Pfam PF00003
PF01094
PRINTS PR01178
PR00248
SUPFAM SSF53822
PROSITE PS00981
PS50259

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0002091

negative regulation of receptor internalization

PMID:21724853[1]

ECO:0000315

P

Figure 5.

complete
CACAO 6636

part_of

GO:0038039

G protein-coupled receptor heterodimeric complex

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O75899

C

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O75899

C

Seeded From UniProt

complete

part_of

GO:0099056

integral component of presynaptic membrane

PMID:14657159[2]

ECO:0006003

electron microscopy evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0099056

integral component of presynaptic membrane

PMID:14657159[2]

ECO:0006003

electron microscopy evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0099056

integral component of presynaptic membrane

PMID:14657159[2]

ECO:0001232

microscopy evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0099056

integral component of presynaptic membrane

PMID:14657159[2]

ECO:0001232

microscopy evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0099055

integral component of postsynaptic membrane

PMID:14657159[2]

ECO:0006003

electron microscopy evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0099055

integral component of postsynaptic membrane

PMID:14657159[2]

ECO:0006003

electron microscopy evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0099055

integral component of postsynaptic membrane

PMID:14657159[2]

ECO:0001232

microscopy evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0099055

integral component of postsynaptic membrane

PMID:14657159[2]

ECO:0001232

microscopy evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0098982

GABA-ergic synapse

PMID:14657159[2]

ECO:0006003

electron microscopy evidence used in manual assertion

C

part_of:(UBERON:0002421)

Seeded From UniProt

complete

part_of

GO:0098982

GABA-ergic synapse

PMID:14657159[2]

ECO:0001232

microscopy evidence used in manual assertion

C

part_of:(UBERON:0002421)

Seeded From UniProt

complete

part_of

GO:0098978

glutamatergic synapse

PMID:14657159[2]

ECO:0006003

electron microscopy evidence used in manual assertion

C

part_of:(UBERON:0002421)

Seeded From UniProt

complete

part_of

GO:0098978

glutamatergic synapse

PMID:14657159[2]

ECO:0001232

microscopy evidence used in manual assertion

C

part_of:(UBERON:0002421)

Seeded From UniProt

complete

involved_in

GO:0007214

gamma-aminobutyric acid signaling pathway

PMID:11389174[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0004965

G protein-coupled GABA receptor activity

PMID:11389174[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0038039

G protein-coupled receptor heterodimeric complex

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0260446
PANTHER:PTN000828857
UniProtKB:A0A0B4LHR4
UniProtKB:O75899
UniProtKB:Q9UBS5

C

Seeded From UniProt

complete

involved_in

GO:0007214

gamma-aminobutyric acid signaling pathway

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0260446
MGI:MGI:1860139
PANTHER:PTN000054983
RGD:619864
UniProtKB:A0A0B4LHR4
UniProtKB:O75899
UniProtKB:Q9UBS5
dictyBase:DDB_G0291356

P

Seeded From UniProt

complete

enables

GO:0004965

G protein-coupled GABA receptor activity

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0260446
PANTHER:PTN000054983
RGD:619864
RGD:621537
UniProtKB:A0A0B4LHR4
UniProtKB:O75899
UniProtKB:Q9UBS5
WB:WBGene00021528
WB:WBGene00022675
dictyBase:DDB_G0291356

F

Seeded From UniProt

complete

enables

GO:0004930

G protein-coupled receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000337
InterPro:IPR017978
InterPro:IPR017979

F

Seeded From UniProt

complete

enables

GO:0004965

G protein-coupled GABA receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002455
InterPro:IPR002457

F

Seeded From UniProt

complete

involved_in

GO:0007186

G protein-coupled receptor signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000337
InterPro:IPR002455
InterPro:IPR002457
InterPro:IPR017978
InterPro:IPR017979

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000337
InterPro:IPR002455
InterPro:IPR002457
InterPro:IPR017978
InterPro:IPR017979

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

PMID:11389174[3]

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

involved_in

GO:0007186

G protein-coupled receptor signaling pathway

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0297

P

Seeded From UniProt

complete

part_of

GO:0030054

cell junction

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0965

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0045211

postsynaptic membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0628
UniProtKB-SubCell:SL-0219

C

Seeded From UniProt

complete

involved_in

GO:0007165

signal transduction

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0807

P

Seeded From UniProt

complete

part_of

GO:0045202

synapse

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0770

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0042995

cell projection

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0966

C

Seeded From UniProt

complete

enables

GO:0004930

G protein-coupled receptor activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0297

F

Seeded From UniProt

complete

part_of

GO:0030425

dendrite

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0283

C

Seeded From UniProt

complete

part_of

GO:0043204

perikaryon

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0197

C

Seeded From UniProt

complete

edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ Hannan, S et al. (2011) Gamma-aminobutyric acid type B (GABA(B)) receptor internalization is regulated by the R2 subunit. J. Biol. Chem. 286 24324-35 PubMed GONUTS page
  2. ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 Kulik, A et al. (2003) Subcellular localization of metabotropic GABA(B) receptor subunits GABA(B1a/b) and GABA(B2) in the rat hippocampus. J. Neurosci. 23 11026-35 PubMed GONUTS page
  3. ↑ 3.0 3.1 3.2 Chronwall, BM et al. (2001) Constitutive expression of functional GABA(B) receptors in mIL-tsA58 cells requires both GABA(B(1)) and GABA(B(2)) genes. J. Neurochem. 77 1237-47 PubMed GONUTS page
  4. ↑ 4.0 4.1 4.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
Retrieved from "https://gowiki.tamu.edu/wiki/index.php?title=RAT:GABR2&oldid=5939653"