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RAT:FST
Contents
| Species (Taxon ID) | Rattus norvegicus (Rat). (10116) | |
| Gene Name(s) | Fst | |
| Protein Name(s) | Follistatin
FS Activin-binding protein | |
| External Links | ||
| UniProt | P21674 | |
| EMBL | M31591 M31586 M31587 M31588 M31589 M31590 S58913 | |
| PIR | I57698 | |
| RefSeq | NP_036693.1 | |
| UniGene | Rn.162557 | |
| PDB | 1LR7 1LR8 1LR9 2ARP | |
| PDBsum | 1LR7 1LR8 1LR9 2ARP | |
| ProteinModelPortal | P21674 | |
| SMR | P21674 | |
| IntAct | P21674 | |
| MINT | MINT-1787002 | |
| MEROPS | I01.966 | |
| Ensembl | ENSRNOT00000015680 | |
| GeneID | 24373 | |
| KEGG | rno:24373 | |
| CTD | 10468 | |
| RGD | 2633 | |
| eggNOG | NOG267610 | |
| GeneTree | ENSGT00440000033501 | |
| HOGENOM | HOG000261649 | |
| HOVERGEN | HBG051666 | |
| InParanoid | P21674 | |
| KO | K04661 | |
| OMA | EAVCASD | |
| OrthoDB | EOG7GBFXR | |
| PhylomeDB | P21674 | |
| TreeFam | TF106409 | |
| Reactome | REACT_198273 | |
| EvolutionaryTrace | P21674 | |
| NextBio | 603119 | |
| PRO | PR:P21674 | |
| Proteomes | UP000002494 | |
| ExpressionAtlas | P21674 | |
| Genevestigator | P21674 | |
| GO | GO:0005737 GO:0005576 GO:0005634 GO:0048185 GO:0043395 GO:0030509 GO:0008585 GO:0007276 GO:0031069 GO:0002244 GO:0043616 GO:0032926 GO:0045596 GO:0046882 GO:0000122 GO:0042475 GO:0007389 GO:0051798 GO:0001501 | |
| InterPro | IPR003645 IPR015369 IPR002350 IPR017878 | |
| Pfam | PF09289 PF07648 | |
| SMART | SM00274 SM00280 | |
| SUPFAM | SSF57581 | |
| PROSITE | PS51465 PS51364 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0043395 |
heparan sulfate proteoglycan binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005575 |
cellular_component |
ECO:0000307 |
no biological data found used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0051798 |
positive regulation of hair follicle development |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P19883 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0048185 |
activin binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P19883 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0038102 |
activin receptor antagonist activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P19883 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0032926 |
negative regulation of activin receptor signaling pathway |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P19883 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0002244 |
hematopoietic progenitor cell differentiation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P19883 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0000122 |
negative regulation of transcription by RNA polymerase II |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P19883 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0048185 |
activin binding |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0046882 |
negative regulation of follicle-stimulating hormone secretion |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Innis, CA & Hyvönen, M (2003) Crystal structures of the heparan sulfate-binding domain of follistatin. Insights into ligand binding. J. Biol. Chem. 278 39969-77 PubMed GONUTS page
- ↑ Rossmanith, W et al. (2002) Follistatin overexpression in rodent liver tumors: a possible mechanism to overcome activin growth control. Mol. Carcinog. 35 1-5 PubMed GONUTS page
- ↑ Shimasaki, S et al. (1989) Follistatin gene expression in the ovary and extragonadal tissues. Mol. Endocrinol. 3 651-9 PubMed GONUTS page
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