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RAT:DPP6

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Species (Taxon ID) Rattus norvegicus (Rat). (10116)
Gene Name(s) Dpp6
Protein Name(s) Dipeptidyl aminopeptidase-like protein 6

DPPX Dipeptidyl aminopeptidase-related protein Dipeptidyl peptidase 6 Dipeptidyl peptidase IV-like protein Dipeptidyl peptidase VI DPP VI

External Links
UniProt P46101
EMBL M76426
M76427
RefSeq NP_074041.1
UniGene Rn.10076
ProteinModelPortal P46101
SMR P46101
STRING 10116.ENSRNOP00000043113
MEROPS S09.973
PaxDb P46101
PRIDE P46101
GeneID 29272
KEGG rno:29272
CTD 1804
RGD 68402
eggNOG COG1506
HOGENOM HOG000231875
HOVERGEN HBG105877
InParanoid P46101
PhylomeDB P46101
NextBio 608626
PRO PR:P46101
Proteomes UP000002494
Genevestigator P46101
GO GO:0009986
GO:0043025
GO:0008076
GO:0008236
GO:0043268
Gene3D 2.140.10.30
3.40.50.1820
InterPro IPR029058
IPR001375
IPR002469
Pfam PF00930
PF00326
SUPFAM SSF53474

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0090004

positive regulation of establishment of protein localization in plasma membrane

PMID:15671030[1]

ECO:0000314

P

figure 1c shows that DPPX (DPP6) promoted a robust trafficking of Kv4.2 to the plasma membrane. accession #:M76427

complete
CACAO 3610

enables

GO:0015459

potassium channel regulator activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z218

F

Seeded From UniProt

complete

involved_in

GO:1901379

regulation of potassium ion transmembrane transport

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z218

P

Seeded From UniProt

complete

involved_in

GO:0072659

protein localization to plasma membrane

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9Z218

P

Seeded From UniProt

complete

enables

GO:0015459

potassium channel regulator activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P42658

F

Seeded From UniProt

complete

NOT|enables

GO:0008239

dipeptidyl-peptidase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P42658

F

Seeded From UniProt

complete

involved_in

GO:1901379

regulation of potassium ion transmembrane transport

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P42658

P

Seeded From UniProt

complete

involved_in

GO:1903078

positive regulation of protein localization to plasma membrane

PMID:15671030[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0043268

positive regulation of potassium ion transport

PMID:12575952[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0043025

neuronal cell body

PMID:12575952[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

PMID:11173531[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0008076

voltage-gated potassium channel complex

PMID:12575952[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0006508

proteolysis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001375
InterPro:IPR002469

P

Seeded From UniProt

complete

enables

GO:0008236

serine-type peptidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001375

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Zagha, E et al. (2005) DPP10 modulates Kv4-mediated A-type potassium channels. J. Biol. Chem. 280 18853-61 PubMed GONUTS page
  2. 2.0 2.1 2.2 Nadal, MS et al. (2003) The CD26-related dipeptidyl aminopeptidase-like protein DPPX is a critical component of neuronal A-type K+ channels. Neuron 37 449-61 PubMed GONUTS page
  3. Kin, Y et al. (2001) Biosynthesis and characterization of the brain-specific membrane protein DPPX, a dipeptidyl peptidase IV-related protein. J. Biochem. 129 289-95 PubMed GONUTS page